Wrong Resemblance? Role of the Immune System in the Biocompatibility of Nanostructured Materials

Research output: Contribution to book/anthology/report/proceedingBook chapterResearch

DOI

Considerable evidence points to the immune system as a formidable barrier to the proper function of nanomaterials in the body. Results
from both experimental models and clinical applications suggest that one of the major current challenges in nanomedicine is to
permit unhindered circulation of vehicles for drug delivery or tissue repair. Biocompatibility of these vehicles has been sought out by
using materials with a biological origin that ensure low toxicity and biodegradability. However, as discussed in this chapter, the
resemblance between physicochemical properties of such materials and products from microbial organisms prompts a diversified response from the immune system.
Original languageEnglish
Title of host publicationHandbook of Harnessing Biomaterials in Nanomedicine
EditorsDan Peer
Place of publicationSingapore
PublisherJenny Stanford Publishing
Publication yearJan 2021
Edition2
Pages307-33
Chapter10
ISBN (Electronic)9781003125259
DOIs
Publication statusPublished - Jan 2021

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