TY - JOUR
T1 - White matter MRI hyperintensities in a hundred and twenty-nine consecutive migraine patients
AU - Pavese, N.
AU - Nuti, A.
AU - Bibbiani, F.
AU - Lucetti, C.
AU - Bonuccelli, U.
AU - Canapicchi, R.
AU - Collavoli, P.
PY - 1994/1/1
Y1 - 1994/1/1
N2 - The most frequently reported abnormal MRI finding in migraine is the presence of high signal white matter foci (WMF) on long TR images. Recently, WMF have been distinguished in periventricular WMF (PVF), when contiguous to ventricles, and deep WMF (DF), when far from these. DF, but not PVF, appear positively correlated with cerebrovascular risk factors and are called leukoaraiosis. In this study the MRI examination was performed in 129 consecutive migraine patients (83 of them had migraine without aura and 46 migraine with aura). In 19.3% of the migraineurs studied we observed WMF on T2 weighted images strictly localized in the deep white matter (DF). No PVF were observed. These findings were independent of the type of migraine and did not correlate with age, sex, disease duration, or frequency of attacks. The presence in a subgroup of migraineurs of leukoaraiosis (DF), for which a vascular genesis has been hypothesized, suggests that migraine could represent, a cerebrovascular risk factor in these patients.
AB - The most frequently reported abnormal MRI finding in migraine is the presence of high signal white matter foci (WMF) on long TR images. Recently, WMF have been distinguished in periventricular WMF (PVF), when contiguous to ventricles, and deep WMF (DF), when far from these. DF, but not PVF, appear positively correlated with cerebrovascular risk factors and are called leukoaraiosis. In this study the MRI examination was performed in 129 consecutive migraine patients (83 of them had migraine without aura and 46 migraine with aura). In 19.3% of the migraineurs studied we observed WMF on T2 weighted images strictly localized in the deep white matter (DF). No PVF were observed. These findings were independent of the type of migraine and did not correlate with age, sex, disease duration, or frequency of attacks. The presence in a subgroup of migraineurs of leukoaraiosis (DF), for which a vascular genesis has been hypothesized, suggests that migraine could represent, a cerebrovascular risk factor in these patients.
KW - Hyperintensities
KW - leukoaraiosis
KW - migraine
KW - MRI white matter
UR - http://www.scopus.com/inward/record.url?scp=0028134748&partnerID=8YFLogxK
U2 - 10.1046/j.1468-2982.1994.1405342.x
DO - 10.1046/j.1468-2982.1994.1405342.x
M3 - Journal article
C2 - 7828192
AN - SCOPUS:0028134748
SN - 0333-1024
VL - 14
SP - 342
EP - 345
JO - Cephalalgia
JF - Cephalalgia
IS - 5
ER -