What is the utility of urodynamics, including ambulatory, and 24 h monitoring, in predicting upper urinary tract damage in neuro-urological patients and other lower urinary tract dysfunction? ICI-RS 2017

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DOI

  • Angie Rantell, King's College and King's College Hospital
  • ,
  • Yutao Lu
  • Marcio A. Averbeck, Moinhos de Vento Hospital
  • ,
  • Jasmin K. Badawi, Universität Heidelberg
  • ,
  • Kevin Rademakers, Maastricht University
  • ,
  • Tufan Tarcan, Marmara University
  • ,
  • Linda Cardozo, King's College and King's College Hospital
  • ,
  • Jens C. Djurhuus
  • David Castro-Diaz, Hospital Universitario de Canarias

Aims: This article focuses on how, and if, urodynamics can help to identify which kidneys are in danger of deteriorating in function and also gives recommendations for future research. Methods: At the International Consultation on Incontinence-Research Society (ICI-RS) in 2017, a multi—disciplinary group presented a literature search of what is known about the utility of Urodynamics, including ambulatory, and 24 h monitoring, in predicting upper urinary tract damage in neuro-urological patients and other lower urinary tract dysfunctions. Wider discussions regarding knowledge gaps, and ideas for future research ensued and are presented in this paper along with a review of the evidence. Results: The current treatment strategy both in congenital and acquired neurogenic bladder is rather aggressive and successful when addressing hazards to kidney function. This article has highlighted uncertainties concerning the use of 40 cmH2O DLPP and even the lower value of 20. The current literature suggests that patients with spina bifida and those with spinal cord injury have a higher risk of developing upper urinary tract damage and kidney function impairment than those with multiple sclerosis. Conclusions: Future research should focus on less invasive methods to assess the risk to the upper and lower urinary tract such as urine and serum measurements of cytokines that are involved in the pathophysiology of urinary tract impairment.

Original languageEnglish
JournalNeurourology and Urodynamics
Volume37
IssueS4
Pages (from-to)S25-S31
ISSN0733-2467
DOIs
Publication statusPublished - Jun 2018

    Research areas

  • renal function, upper urinary tract, urodynamics

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