Visualization of thermally activated nanocarriers using in situ atomic force microscopy: Nanotechnology

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  • Department of Physics and Astronomy
  • Interdisciplinary Nanoscience Center
  • Department of Molecular Biology
Thermo-responsive nanocarriers aim to improve the delivery of drugs into target tissue by a process of size-mediated deposition activated by thermal stimuli. The direct imaging of thermally-induced changes in nanocarrier morphology was demonstrated using in situ liquid AFM over a nano-scale and temperature range relevant for clinical approaches. In situ AFM proved to be a unique method for investigating the dynamic conformational changes of individual nanoparticles, promoting its application in the future development of stimuli-responsive nanocarriers.
Original languageEnglish
JournalNanotechnology
Volume18
Issue18
ISSN0957-4484
Publication statusPublished - 2007

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