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Visualization of nonlinear classification models in neuroimaging: Signed sensitivity maps

Research output: Contribution to book/anthology/report/proceedingArticle in proceedingsResearchpeer-review

  • Peter Mondrup Rasmussen
  • K.H. Madsen, Technical University of Denmark
  • ,
  • L.K. Hansen, Technical University of Denmark
  • ,
  • T.E. Lund
  • T. Schmah, University of Toronto
  • ,
  • G. Yourganov, Baycrest Centre for Geriatric Care
  • ,
  • S.C. Strother, Baycrest Centre for Geriatric Care
Classification models are becoming increasing popular tools in the analysis of neuroimaging data sets. Besides obtaining good prediction accuracy, a competing goal is to interpret how the classifier works. From a neuroscientific perspective, we are interested in the brain pattern reflecting the underlying neural encoding of an experiment defining multiple brain states. In this relation there is a great desire for the researcher to generate brain maps, that highlight brain locations of importance to the classifiers decisions. Based on sensitivity analysis, we develop further procedures for model visualization. Specifically we focus on the generation of summary maps of a nonlinear classifier, that reveal how the classifier works in different parts of the input domain. Each of the maps includes sign information, unlike earlier related methods. The sign information allows the researcher to assess in which direction the individual locations influence the classification. We illustrate the visualization procedure on a real data from a simple functional magnetic resonance imaging experiment.
Original languageEnglish
Title of host publicationBIOSIGNALS 2012 - Proceedings of the International Conference on Bio-Inspired Systems and Signal Processing
Number of pages10
Publication year1 Jan 2012
Pages254-263
Publication statusPublished - 1 Jan 2012

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