VHS virus - present situation

Niels Jørgen Olesen, Helle Frank Skall

Research output: Contribution to conferenceConference abstract for conferenceResearch

Abstract

Geographic distribution:
VHSV can be divided into 4 genotypes and at least 8 subtypes and there is a close linkage between genotypes, geographic range and affected fish species. VHS is still only reported from the Northern hemisphere- and while countries like Denmark, Norway and England have freed themselves for VHS, several countries are still struggling with the disease. An update on the recent VHS outbreaks in rainbow trout in Iran, in olive flounder in Korea, in wrasse in Scotland, in turbot in Turkey, in a number of fish species in the great lakes in USA and Canada, and a general overview of the worldwide distribution of the disease will be given.
Virus evolution:
Recent studies indicate that only a few amino acid changes in the structural proteins of VHSV can change the virulence patterns significantly, thereby coming closer to assessing the risk of none to low virulent viruses becoming high virulent. Virulence factors both depend on the ability of VHSV to enter a cell and on the speed and efficiency of virus replication in the cells. Apparently the viral nucleocapsid protein plays a very important role for the later and seems to be the target for determination of a virulence marker.
Translated title of the contributionVHS virus - den nuværende situation
Original languageEnglish
Publication date18 Nov 2015
Number of pages1
Publication statusPublished - 18 Nov 2015
EventDAFINET and ProFish Workshop: Pathogen-host interactins and vaccine effects - Københavns Universitet, Frederiksberg Campus, København, Denmark
Duration: 17 Nov 201518 Nov 2015

Workshop

WorkshopDAFINET and ProFish Workshop
LocationKøbenhavns Universitet, Frederiksberg Campus
Country/TerritoryDenmark
CityKøbenhavn
Period17/11/201518/11/2015

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