Abstract
Geographic distribution:
VHSV can be divided into 4 genotypes and at least 8 subtypes and there is a close linkage between genotypes, geographic range and affected fish species. VHS is still only reported from the Northern hemisphere- and while countries like Denmark, Norway and England have freed themselves for VHS, several countries are still struggling with the disease. An update on the recent VHS outbreaks in rainbow trout in Iran, in olive flounder in Korea, in wrasse in Scotland, in turbot in Turkey, in a number of fish species in the great lakes in USA and Canada, and a general overview of the worldwide distribution of the disease will be given.
Virus evolution:
Recent studies indicate that only a few amino acid changes in the structural proteins of VHSV can change the virulence patterns significantly, thereby coming closer to assessing the risk of none to low virulent viruses becoming high virulent. Virulence factors both depend on the ability of VHSV to enter a cell and on the speed and efficiency of virus replication in the cells. Apparently the viral nucleocapsid protein plays a very important role for the later and seems to be the target for determination of a virulence marker.
VHSV can be divided into 4 genotypes and at least 8 subtypes and there is a close linkage between genotypes, geographic range and affected fish species. VHS is still only reported from the Northern hemisphere- and while countries like Denmark, Norway and England have freed themselves for VHS, several countries are still struggling with the disease. An update on the recent VHS outbreaks in rainbow trout in Iran, in olive flounder in Korea, in wrasse in Scotland, in turbot in Turkey, in a number of fish species in the great lakes in USA and Canada, and a general overview of the worldwide distribution of the disease will be given.
Virus evolution:
Recent studies indicate that only a few amino acid changes in the structural proteins of VHSV can change the virulence patterns significantly, thereby coming closer to assessing the risk of none to low virulent viruses becoming high virulent. Virulence factors both depend on the ability of VHSV to enter a cell and on the speed and efficiency of virus replication in the cells. Apparently the viral nucleocapsid protein plays a very important role for the later and seems to be the target for determination of a virulence marker.
Translated title of the contribution | VHS virus - den nuværende situation |
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Original language | English |
Publication date | 18 Nov 2015 |
Number of pages | 1 |
Publication status | Published - 18 Nov 2015 |
Event | DAFINET and ProFish Workshop: Pathogen-host interactins and vaccine effects - Københavns Universitet, Frederiksberg Campus, København, Denmark Duration: 17 Nov 2015 → 18 Nov 2015 |
Workshop
Workshop | DAFINET and ProFish Workshop |
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Location | Københavns Universitet, Frederiksberg Campus |
Country/Territory | Denmark |
City | København |
Period | 17/11/2015 → 18/11/2015 |