TY - JOUR
T1 - Validity and reliability of VO2-max testing in persons with Parkinson's disease.
AU - Jensen, Frederik Bonde
AU - Dalgas, Ulrik
AU - Brincks, John
AU - Langeskov-Christensen, Martin
N1 - Copyright © 2023 Elsevier Ltd. All rights reserved.
PY - 2023/4
Y1 - 2023/4
N2 - INTRODUCTION: Direct whole body assessment of maximal oxygen consumption (VO
2-max test) is considered the gold standard when assessing cardiorespiratory fitness (VO
2-max) in healthy people. VO
2-max is also an important health and performance indicator for persons with Parkinson's disease (pwPD) and is often used when prescribing exercise and evaluating aerobic exercise interventions. However, no study has examined the content validity of the VO
2-max test in pwPD as well as the test-retest reliability (i.e., day-to-day variation) in both the ON and OFF medication state. Therefore, the present study investigated the content validity and test-retest reliability of the VO
2-max test in pwPD both ON and OFF medication.
METHODS: Twenty pwPD completed four VO
2-max tests (two tests ON and two tests OFF medication), in a randomized order, separated by four to sixteen days. The first tests ON and OFF medication were used to assess content validity based on attainment of five pre-defined end-criteria (one primary and four secondary). Reliability was examined by intraclass correlation coefficients (ICC) and the day-to-day variation of the two ON and OFF medication tests.
RESULTS: In pwPD, 50% and 60% attained the primary end-criterion ON and OFF medication, respectively. A higher proportion (i.e., 70-90%) attained the secondary end-criteria both ON and OFF medication with no difference between medication states. Day-to-day variations were 1.2 and 1.8 ml O
2/kg/min, while ICC
2.1 were 0.97 (95%-CI: 0.92; 0.99) and 0.96 (95%-CI: 0.90; 0.98) ON and OFF medication, respectively.
CONCLUSION: The VO
2-max test has an acceptable content validity and excellent day-to-day reliability ON and OFF medication in pwPD.
AB - INTRODUCTION: Direct whole body assessment of maximal oxygen consumption (VO
2-max test) is considered the gold standard when assessing cardiorespiratory fitness (VO
2-max) in healthy people. VO
2-max is also an important health and performance indicator for persons with Parkinson's disease (pwPD) and is often used when prescribing exercise and evaluating aerobic exercise interventions. However, no study has examined the content validity of the VO
2-max test in pwPD as well as the test-retest reliability (i.e., day-to-day variation) in both the ON and OFF medication state. Therefore, the present study investigated the content validity and test-retest reliability of the VO
2-max test in pwPD both ON and OFF medication.
METHODS: Twenty pwPD completed four VO
2-max tests (two tests ON and two tests OFF medication), in a randomized order, separated by four to sixteen days. The first tests ON and OFF medication were used to assess content validity based on attainment of five pre-defined end-criteria (one primary and four secondary). Reliability was examined by intraclass correlation coefficients (ICC) and the day-to-day variation of the two ON and OFF medication tests.
RESULTS: In pwPD, 50% and 60% attained the primary end-criterion ON and OFF medication, respectively. A higher proportion (i.e., 70-90%) attained the secondary end-criteria both ON and OFF medication with no difference between medication states. Day-to-day variations were 1.2 and 1.8 ml O
2/kg/min, while ICC
2.1 were 0.97 (95%-CI: 0.92; 0.99) and 0.96 (95%-CI: 0.90; 0.98) ON and OFF medication, respectively.
CONCLUSION: The VO
2-max test has an acceptable content validity and excellent day-to-day reliability ON and OFF medication in pwPD.
KW - Aerobic training
KW - Cardiopulmonary exercise testing
KW - Exercise therapy
KW - Rehabilitation
U2 - 10.1016/j.parkreldis.2023.105324
DO - 10.1016/j.parkreldis.2023.105324
M3 - Journal article
C2 - 36827950
SN - 1353-8020
VL - 109
JO - Parkinsonism & Related Disorders
JF - Parkinsonism & Related Disorders
M1 - 105324
ER -