Validity and reliability of linear encoder muscle power testing in persons with Parkinson's disease

TY - JOUR

T1 - Validity and reliability of linear encoder muscle power testing in persons with Parkinson's disease

AU - Bonde-Jensen, Frederik

AU - Dalgas, Ulrik

AU - Hvid, Lars Grøndahl

AU - Langeskov-Christensen, Martin

PY - 2024/5

Y1 - 2024/5

N2 - OBJECTIVE: To investigate the construct validity ON medication and the reliability both ON and OFF medication of linear encoder muscle power testing in persons with Parkinson's disease (pwPD).DESIGN: A study using baseline data from one randomized controlled trial (study 1) and one cohort study (study 2).SETTING: University exercise lab.PARTICIPANTS: Study 1: 35 healthy controls and 70 pwPD. Study 2: 20 pwPD.INTERVENTION: Study 1: baseline data. Study 2: 4 chair rise tests (2 ON and 2 OFF medication), in a randomized order, separated by 4 to 16 days.MAIN MEASURES: Linear encoder data were collected from a chair rise test. Known groups validity and convergent validity (i.e., construct validity) were assessed by comparing peak power between pwPD and healthy controls and associations between peak power and functional performance (i.e., 6-Min Walk Test, Timed Up and Go Test, Six-Spot Step Test), respectively. Reliability was assessed as day-to-day variation and by intraclass correlation coefficients.RESULTS: Peak power was comparable between pwPD and healthy controls (-7.2%, p = 0.17), but lower in moderately impaired pwPD compared to mildly impaired pwPD (-27%, p < 0.01) and healthy controls (-23%, p < 0.01). Moderate to strong associations were observed between peak power and functional performance (r 2 = 0.44-0.51). Day-to-day variation ON and OFF medication were 1.0 and 1.3 W/kg, respectively, while intraclass correlation coefficients were 0.95 (0.87;0.98) and 0.93 (0.82;0.97), respectively. CONCLUSION: Linear encoder muscle power testing shows inconsistent known groups validity, acceptable convergent validity ON medication, and excellent day-to-day reliability ON and OFF medication in pwPD.

AB - OBJECTIVE: To investigate the construct validity ON medication and the reliability both ON and OFF medication of linear encoder muscle power testing in persons with Parkinson's disease (pwPD).DESIGN: A study using baseline data from one randomized controlled trial (study 1) and one cohort study (study 2).SETTING: University exercise lab.PARTICIPANTS: Study 1: 35 healthy controls and 70 pwPD. Study 2: 20 pwPD.INTERVENTION: Study 1: baseline data. Study 2: 4 chair rise tests (2 ON and 2 OFF medication), in a randomized order, separated by 4 to 16 days.MAIN MEASURES: Linear encoder data were collected from a chair rise test. Known groups validity and convergent validity (i.e., construct validity) were assessed by comparing peak power between pwPD and healthy controls and associations between peak power and functional performance (i.e., 6-Min Walk Test, Timed Up and Go Test, Six-Spot Step Test), respectively. Reliability was assessed as day-to-day variation and by intraclass correlation coefficients.RESULTS: Peak power was comparable between pwPD and healthy controls (-7.2%, p = 0.17), but lower in moderately impaired pwPD compared to mildly impaired pwPD (-27%, p < 0.01) and healthy controls (-23%, p < 0.01). Moderate to strong associations were observed between peak power and functional performance (r 2 = 0.44-0.51). Day-to-day variation ON and OFF medication were 1.0 and 1.3 W/kg, respectively, while intraclass correlation coefficients were 0.95 (0.87;0.98) and 0.93 (0.82;0.97), respectively. CONCLUSION: Linear encoder muscle power testing shows inconsistent known groups validity, acceptable convergent validity ON medication, and excellent day-to-day reliability ON and OFF medication in pwPD.

KW - exercise therapy

KW - muscle power exercise testing

KW - rehabilitation

KW - resistance training

KW - Reproducibility of Results

KW - Humans

KW - Muscles

KW - Time and Motion Studies

KW - Parkinson Disease/diagnosis

KW - Postural Balance

KW - Cohort Studies

UR - http://www.scopus.com/inward/record.url?scp=85181710301&partnerID=8YFLogxK

U2 - 10.1177/02692155231224987

DO - 10.1177/02692155231224987

M3 - Journal article

C2 - 38193269

SN - 0269-2155

VL - 38

SP - 678

EP - 687

JO - Clinical Rehabilitation

JF - Clinical Rehabilitation

IS - 5

ER -