Validation of an semi-automated multi component method using protein precipitation LC-MS-MS for the analysis of whole blood samples

Research output: Contribution to conferencePosterResearch

BACKGROUND: Solid phase extraction (SPE) are one of many multi-component methods, but can be very time-consuming and labour-intensive. Protein precipitation is, on the other hand, a much simpler and faster sample pre-treatment than SPE, and protein precipitation also has the ability to cover a wider range of components.
AIM: The aim was to develop a robust semi-automated analytical method for whole blood samples based on a protein precipitation method already used in the lab (Sørensen and Hasselstrøm, 2013). The setup should improve the speed, robustness, and reliability of anteand post-mortem whole blood sample preparation for toxicological analysis; from the primary sample tube to a 96-deepwell plate ready for injection on the liquid chromatography mass
spectrometry (LC-MS/MS).
Original languageDanish
Publication year2017
Publication statusPublished - 2017
Event2017 Joint meeting of the Society og Forensic Toxicologists and The International Association of Forensic Toxicologists: Oprindelig planlagt sept 9-14, 2017, afholdt jan 7-11, 2018 - Waldorf Astoria Boca Raton Resort, Boca Raton, United States
Duration: 7 Jan 201811 Jan 2018
http://www.soft-tox.org/scientific-sessions

Conference

Conference2017 Joint meeting of the Society og Forensic Toxicologists and The International Association of Forensic Toxicologists
LocationWaldorf Astoria Boca Raton Resort
CountryUnited States
CityBoca Raton
Period07/01/201811/01/2018
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