Uric Acid: A Less-than-Perfect Probe for Singlet Oxygen

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Standard

Uric Acid: A Less-than-Perfect Probe for Singlet Oxygen. / Bregnhøj, Mikkel; Dichmann, Lea; McLoughlin, Ciaran K.; Westberg, Michael; Ogilby, Peter R.

In: Photochemistry and Photobiology, Vol. 95, No. 1, 2019, p. 202-210.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

Harvard

Bregnhøj, M, Dichmann, L, McLoughlin, CK, Westberg, M & Ogilby, PR 2019, 'Uric Acid: A Less-than-Perfect Probe for Singlet Oxygen', Photochemistry and Photobiology, vol. 95, no. 1, pp. 202-210. https://doi.org/10.1111/php.12971

APA

Bregnhøj, M., Dichmann, L., McLoughlin, C. K., Westberg, M., & Ogilby, P. R. (2019). Uric Acid: A Less-than-Perfect Probe for Singlet Oxygen. Photochemistry and Photobiology, 95(1), 202-210. https://doi.org/10.1111/php.12971

CBE

Bregnhøj M, Dichmann L, McLoughlin CK, Westberg M, Ogilby PR. 2019. Uric Acid: A Less-than-Perfect Probe for Singlet Oxygen. Photochemistry and Photobiology. 95(1):202-210. https://doi.org/10.1111/php.12971

MLA

Vancouver

Bregnhøj M, Dichmann L, McLoughlin CK, Westberg M, Ogilby PR. Uric Acid: A Less-than-Perfect Probe for Singlet Oxygen. Photochemistry and Photobiology. 2019;95(1):202-210. https://doi.org/10.1111/php.12971

Author

Bregnhøj, Mikkel ; Dichmann, Lea ; McLoughlin, Ciaran K. ; Westberg, Michael ; Ogilby, Peter R. / Uric Acid: A Less-than-Perfect Probe for Singlet Oxygen. In: Photochemistry and Photobiology. 2019 ; Vol. 95, No. 1. pp. 202-210.

Bibtex

@article{6fc1334a69d54a3a89365f3ab80eed7c,
title = "Uric Acid: A Less-than-Perfect Probe for Singlet Oxygen",
abstract = "Uric acid and/or its monoanion has long been used as chemical-trapping agents to demonstrate the presence of singlet oxygen, O2(a1Δg), in aqueous systems. “Oxidative bleaching” of uric acid, generally monitored through changes in the uric acid absorption spectrum, is often used in support of claims for the intermediacy of O2(a1Δg). The bleaching of uric acid has also been used to quantify photosensitized O2(a1Δg) yields in selected systems. Unfortunately, experiments performed to these ends often neglect processes and phenomena that can influence the results obtained. For the present study, we experimentally examined the behavior of uric acid under a variety of conditions relevant to the photoinitiated creation and subsequent removal of O2(a1Δg). Although the oxidative destruction of uric acid can indeed be a useful tool in some cases, we conclude that caution must be exercised such as not to incorrectly interpret the data obtained.",
author = "Mikkel Bregnh{\o}j and Lea Dichmann and McLoughlin, {Ciaran K.} and Michael Westberg and Ogilby, {Peter R.}",
note = "this article is part of a Special Issue celebrating Photochemistry and Photobiology's 55th Anniversary.",
year = "2019",
doi = "10.1111/php.12971",
language = "English",
volume = "95",
pages = "202--210",
journal = "Photochemistry and Photobiology",
issn = "0031-8655",
publisher = "Wiley-Blackwell Publishing, Inc",
number = "1",

}

RIS

TY - JOUR

T1 - Uric Acid: A Less-than-Perfect Probe for Singlet Oxygen

AU - Bregnhøj, Mikkel

AU - Dichmann, Lea

AU - McLoughlin, Ciaran K.

AU - Westberg, Michael

AU - Ogilby, Peter R.

N1 - this article is part of a Special Issue celebrating Photochemistry and Photobiology's 55th Anniversary.

PY - 2019

Y1 - 2019

N2 - Uric acid and/or its monoanion has long been used as chemical-trapping agents to demonstrate the presence of singlet oxygen, O2(a1Δg), in aqueous systems. “Oxidative bleaching” of uric acid, generally monitored through changes in the uric acid absorption spectrum, is often used in support of claims for the intermediacy of O2(a1Δg). The bleaching of uric acid has also been used to quantify photosensitized O2(a1Δg) yields in selected systems. Unfortunately, experiments performed to these ends often neglect processes and phenomena that can influence the results obtained. For the present study, we experimentally examined the behavior of uric acid under a variety of conditions relevant to the photoinitiated creation and subsequent removal of O2(a1Δg). Although the oxidative destruction of uric acid can indeed be a useful tool in some cases, we conclude that caution must be exercised such as not to incorrectly interpret the data obtained.

AB - Uric acid and/or its monoanion has long been used as chemical-trapping agents to demonstrate the presence of singlet oxygen, O2(a1Δg), in aqueous systems. “Oxidative bleaching” of uric acid, generally monitored through changes in the uric acid absorption spectrum, is often used in support of claims for the intermediacy of O2(a1Δg). The bleaching of uric acid has also been used to quantify photosensitized O2(a1Δg) yields in selected systems. Unfortunately, experiments performed to these ends often neglect processes and phenomena that can influence the results obtained. For the present study, we experimentally examined the behavior of uric acid under a variety of conditions relevant to the photoinitiated creation and subsequent removal of O2(a1Δg). Although the oxidative destruction of uric acid can indeed be a useful tool in some cases, we conclude that caution must be exercised such as not to incorrectly interpret the data obtained.

UR - http://www.scopus.com/inward/record.url?scp=85052474077&partnerID=8YFLogxK

U2 - 10.1111/php.12971

DO - 10.1111/php.12971

M3 - Journal article

VL - 95

SP - 202

EP - 210

JO - Photochemistry and Photobiology

JF - Photochemistry and Photobiology

SN - 0031-8655

IS - 1

ER -