Unraveling the neutral and polar lipidome of Nordic brown macroalgae: A sustainable source of functional lipids

TY - JOUR

T1 - Unraveling the neutral and polar lipidome of Nordic brown macroalgae

T2 - A sustainable source of functional lipids

AU - Pham, Thu H.

AU - Thomas, Raymond

AU - Schwab, Clarissa

AU - Martinez, Mario M.

AU - Vidal, Natalia P.

PY - 2024/11/30

Y1 - 2024/11/30

N2 - Brown macroalgae represent a sustainable and abundant source of lipids with acknowledged functional and health benefits. Nonetheless, macroalgae lipidome has been poorly unraveled due to lipids complex structural and chemical diversity. In this study, a comprehensive lipidomic analysis was performed in four macroalgae: Saccharina latissima, Fucus vesiculosus, Fucus serratus and the invasive Sargassum muticum, using HILIC-C30RP-HRMS. Neutral lipids (tri-, di-glycerides) comprised 72–82% of total lipids (TL) with a highly unsaturation profile (27–49% depending on species). The polar lipidome comprised glycolipids, phospholipids, betaine lipids and sphingolipids with varied content among macroalgae. S. latissima displayed the greatest level of glycolipids (23% of TL), by contrast with the dominance of long-chain polyunsaturated betaine lipids (10–18% of TL) in the other species, particularly in S. muticum. Phospholipids and sphingolipids were detected in low abundance (<1.7% of TL). This study elevated the potential of brown macroalgae as an emerging reservoir of bioactive lipids with nutritional relevance.

AB - Brown macroalgae represent a sustainable and abundant source of lipids with acknowledged functional and health benefits. Nonetheless, macroalgae lipidome has been poorly unraveled due to lipids complex structural and chemical diversity. In this study, a comprehensive lipidomic analysis was performed in four macroalgae: Saccharina latissima, Fucus vesiculosus, Fucus serratus and the invasive Sargassum muticum, using HILIC-C30RP-HRMS. Neutral lipids (tri-, di-glycerides) comprised 72–82% of total lipids (TL) with a highly unsaturation profile (27–49% depending on species). The polar lipidome comprised glycolipids, phospholipids, betaine lipids and sphingolipids with varied content among macroalgae. S. latissima displayed the greatest level of glycolipids (23% of TL), by contrast with the dominance of long-chain polyunsaturated betaine lipids (10–18% of TL) in the other species, particularly in S. muticum. Phospholipids and sphingolipids were detected in low abundance (<1.7% of TL). This study elevated the potential of brown macroalgae as an emerging reservoir of bioactive lipids with nutritional relevance.

KW - Betaine lipids

KW - Biomass valorization

KW - Brown macroalgae

KW - Neutral and polar functional lipids

KW - Sargassum muticum

UR - http://www.scopus.com/inward/record.url?scp=85198975286&partnerID=8YFLogxK

U2 - 10.1016/j.foodchem.2024.140415

DO - 10.1016/j.foodchem.2024.140415

M3 - Journal article

C2 - 39032363

AN - SCOPUS:85198975286

SN - 0308-8146

VL - 459

JO - Food Chemistry

JF - Food Chemistry

M1 - 140415

ER -