Understanding Nod factor signalling paves the way for targeted engineering in legumes and non-legumes

TY - JOUR

T1 - Understanding Nod factor signalling paves the way for targeted engineering in legumes and non-legumes

AU - Krönauer, Christina

AU - Radutoiu, Simona

PY - 2021/8

Y1 - 2021/8

N2 - Legumes evolved LysM receptors for recognition of rhizobial Nod factors and initiation of signalling pathways for nodule organogenesis and infection. Intracellularly hosted bacteria are supplied with carbon resources in exchange for fixed nitrogen. Nod factor recognition is crucial for initial signalling, but is reiterated in growing roots initiating novel symbiotic events, and in developing primordia until symbiosis is well-established. Understanding how this signalling coordinates the entire process from cellular to plant level is key for de novo engineering in non-legumes and for improved efficiency in legumes. Here we discuss how recent studies bring new insights into molecular determinants of specificity and sensitivity in Nod factor signalling in legumes, and present some of the unknowns and challenges for engineering.

AB - Legumes evolved LysM receptors for recognition of rhizobial Nod factors and initiation of signalling pathways for nodule organogenesis and infection. Intracellularly hosted bacteria are supplied with carbon resources in exchange for fixed nitrogen. Nod factor recognition is crucial for initial signalling, but is reiterated in growing roots initiating novel symbiotic events, and in developing primordia until symbiosis is well-established. Understanding how this signalling coordinates the entire process from cellular to plant level is key for de novo engineering in non-legumes and for improved efficiency in legumes. Here we discuss how recent studies bring new insights into molecular determinants of specificity and sensitivity in Nod factor signalling in legumes, and present some of the unknowns and challenges for engineering.

UR - http://www.scopus.com/inward/record.url?scp=85101979238&partnerID=8YFLogxK

U2 - 10.1016/j.pbi.2021.102026

DO - 10.1016/j.pbi.2021.102026

M3 - Review

C2 - 33684882

AN - SCOPUS:85101979238

SN - 1369-5266

VL - 62

JO - Current Opinion in Plant Biology

JF - Current Opinion in Plant Biology

M1 - 102026

ER -