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Ultraporous interweaving electrospun microfibers from PCL-PEO binary blends and their cellular response

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Production of one dimensional nanomaterials with secondary morphology exhibiting unique functions is challenging. Here we report that a nanoscale immiscible polymer blend solution the electrojet can assemble into ultraporous interweaving microfibers. This intriguingly novel morphology originated from a blend of polycaprolactone (PCL) and polyethylene oxide (PEO) in a DCM-DMF mixed solution when the ratio between each component reached a threshold and when the electrospinning parameters were delicately controlled. We further investigated their influence on cell infiltration and colonization. The hierarchical porosity enhanced cell infiltration and proliferation significantly.

Original languageEnglish
Title of host publicationNART 2015-Nanofibers, Applications and Related Technologies
EditorsS Petrik
Number of pages3
PublisherTECHNICAL UNIVERSITY LIBEREC
Publication year2015
Pages143-145
Publication statusPublished - 2015
EventProceedings of Nanofibers, Applications and Related Technologies NART - Liberec, Czech Republic
Duration: 31 Aug 20152 Sep 2015

Conference

ConferenceProceedings of Nanofibers, Applications and Related Technologies NART
LandCzech Republic
ByLiberec
Periode31/08/201502/09/2015

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