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Topical valrubicin application reduces skin inflammation in murine models

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  • E Hauge
  • Helle Christiansen, Denmark
  • C Rosada, Denmark
  • E de Darkó
  • ,
  • T N Dam, Denmark
  • K Stenderup
Valrubicin is a cytostatic anthracycline analogue, lacking toxicity by skin and tissue contact, and represents a new drug with potential for topical treatment of psoriasis and nonmelanoma skin cancer (NMSC); the beneficial effects have been partly explained by its antiproliferative and proapoptotic characteristics.
Original languageEnglish
JournalBritish Journal of Dermatology
Pages (from-to)288-95
Number of pages8
Publication statusPublished - 2012

    Research areas

  • Acute Disease, Administration, Cutaneous, Animals, Anti-Inflammatory Agents, Chronic Disease, Cytokines, Dermatitis, Irritant, Disease Models, Animal, Doxorubicin, Irritants, Mice, Mice, Inbred C57BL, Neutrophil Infiltration, Tetradecanoylphorbol Acetate

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