Topical treatment of psoriasis: questionnaire results on topical therapy as long-term continuous treatment and use on specific body sites

TY - JOUR

T1 - Topical treatment of psoriasis

T2 - questionnaire results on topical therapy as long-term continuous treatment and use on specific body sites

AU - Hoegsberg, T

AU - Iversen, L

AU - Lange, M M

AU - Bissonette, R

AU - Carvalho, A V E

AU - van de Kerkhof, P C

AU - Kirby, B

AU - Kleyn, C E

AU - van der Walt, J M

AU - Wu, J J

AU - Lynde, C W

PY - 2021

Y1 - 2021

N2 - Background: Currently, no formalized international consensus guidelines exist to direct optimal topical treatment including long-term treatment.Objective: In this survey, we aim to examine if and which topicals are used in clinical practice in long-term continuous treatment of psoriasis and how topicals are used in treating specific sites of the body.Methods: A questionnaire was distributed electronically to dermatologists from the International Psoriasis Council (IPC) representing 26 countries.Results: The top three topicals used across all severities of disease were topical corticosteroids, vitamin D analogs, and potent topical corticosteroids in combination with vitamin D analogs. On locations where the skin is thin, flexural and genital psoriasis, lower potency topical corticosteroids were used, whereas on other sites, in particular in palmoplantar psoriasis, superpotent topical corticosteroids and combination vitamin D analogs/corticosteroids were used.Conclusions: It is relevant to optimize localized therapy for all severities of psoriasis reconciling disease activity (stable vs. unstable disease), localization of the lesions and the individual patient and his/her perspectives on disease control. Topical therapies are valuable treatments for classical mild disease and may have a position in some patients with more severe manifestations.

AB - Background: Currently, no formalized international consensus guidelines exist to direct optimal topical treatment including long-term treatment.Objective: In this survey, we aim to examine if and which topicals are used in clinical practice in long-term continuous treatment of psoriasis and how topicals are used in treating specific sites of the body.Methods: A questionnaire was distributed electronically to dermatologists from the International Psoriasis Council (IPC) representing 26 countries.Results: The top three topicals used across all severities of disease were topical corticosteroids, vitamin D analogs, and potent topical corticosteroids in combination with vitamin D analogs. On locations where the skin is thin, flexural and genital psoriasis, lower potency topical corticosteroids were used, whereas on other sites, in particular in palmoplantar psoriasis, superpotent topical corticosteroids and combination vitamin D analogs/corticosteroids were used.Conclusions: It is relevant to optimize localized therapy for all severities of psoriasis reconciling disease activity (stable vs. unstable disease), localization of the lesions and the individual patient and his/her perspectives on disease control. Topical therapies are valuable treatments for classical mild disease and may have a position in some patients with more severe manifestations.

KW - Psoriasis

KW - body surface area

KW - topical corticosteroids

KW - topical therapy

KW - GUIDELINES

KW - Humans

KW - Psoriasis/drug therapy

KW - Male

KW - Dermatologic Agents/therapeutic use

KW - Female

KW - Surveys and Questionnaires

KW - Vitamin D/therapeutic use

KW - Administration, Topical

U2 - 10.1080/09546634.2020.1724250

DO - 10.1080/09546634.2020.1724250

M3 - Review

C2 - 31996058

SN - 0954-6634

VL - 32

SP - 916

EP - 921

JO - Journal of Dermatological Treatment

JF - Journal of Dermatological Treatment

IS - 8

ER -