The impact of mindfulness-based interventions on brain activity: A systematic review of functional magnetic resonance imaging studies

Katherine S Young, Anne Maj van der Velden, Michelle G Craske, Karen Johanne Pallesen, Lone Fjorback, Andreas Roepstorff, Christine E Parsons

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

128 Citations (Scopus)

Abstract

Mindfulness-based interventions are increasingly used in the treatment and prevention of mental health conditions. Despite this, the mechanisms of change for such interventions are only beginning to be understood, with a number of recent studies assessing changes in brain activity. The aim of this systematic review was to assess changes in brain functioning associated with manualised 8-session mindfulness interventions. Searches of PubMed and Scopus databases resulted in 39 papers, 7 of which were eligible for inclusion. The most consistent longitudinal effect observed was increased insular cortex activity following mindfulness-based interventions. In contrast to previous reviews, we did not find robust evidence for increased activity in specific prefrontal cortex sub-regions. These findings suggest that mindfulness interventions are associated with changes in functioning of the insula, plausibly impacting awareness of internal reactions ‘in-the-moment’. The studies reviewed here demonstrated a variety of effects across populations and tasks, pointing to the need for greater consistency in future study design.

Original languageEnglish
JournalNeuroscience & Biobehavioral Reviews
Volume84
IssueJanuary
Pages (from-to)424-433
Number of pages10
ISSN0149-7634
DOIs
Publication statusPublished - 1 Jan 2018

Keywords

  • Emotion regulation
  • Insula
  • Mindfulness
  • Mindfulness-based interventions
  • fMRI

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