The function and architecture of DEAH/RHA helicases

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The function and architecture of DEAH/RHA helicases. / He, Yangzi; Andersen, Gregers Rom; Nielsen, Klaus Hvid.

In: BioMolecular Concepts, Vol. 2, No. 4, 07.2012, p. 315-326.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

Harvard

He, Y, Andersen, GR & Nielsen, KH 2012, 'The function and architecture of DEAH/RHA helicases', BioMolecular Concepts, vol. 2, no. 4, pp. 315-326. https://doi.org/10.1515/bmc.2011.024

APA

He, Y., Andersen, G. R., & Nielsen, K. H. (2012). The function and architecture of DEAH/RHA helicases. BioMolecular Concepts, 2(4), 315-326. https://doi.org/10.1515/bmc.2011.024

CBE

MLA

He, Yangzi, Gregers Rom Andersen and Klaus Hvid Nielsen. "The function and architecture of DEAH/RHA helicases". BioMolecular Concepts. 2012, 2(4). 315-326. https://doi.org/10.1515/bmc.2011.024

Vancouver

Author

He, Yangzi ; Andersen, Gregers Rom ; Nielsen, Klaus Hvid. / The function and architecture of DEAH/RHA helicases. In: BioMolecular Concepts. 2012 ; Vol. 2, No. 4. pp. 315-326.

Bibtex

@article{fd8db5a3df464ca5b3b2b47698357f40,
title = "The function and architecture of DEAH/RHA helicases",
abstract = "Helicases are ubiquitous enzymes that participate in every aspect of nucleic acid metabolism. The DEAH/RHA family of helicases are involved in a variety of cellular processes including transcriptional and translational regulation, pre-mRNA splicing, pre-rRNA processing, mRNA export and decay, in addition to the innate immune response. Recently, the first crystal structures of a DEAH/RHA helicase unveiled the unique structural features of this helicase family. These structures furthermore illuminate the molecular mechanism of these proteins and provide a framework for analysis of their interaction with nucleic acids, regulatory proteins and large macromolecular complexes.",
author = "Yangzi He and Andersen, {Gregers Rom} and Nielsen, {Klaus Hvid}",
year = "2012",
month = jul,
doi = "10.1515/bmc.2011.024",
language = "English",
volume = "2",
pages = "315--326",
journal = "BioMolecular Concepts",
issn = "1868-5021",
publisher = "Walterde Gruyter GmbH",
number = "4",

}

RIS

TY - JOUR

T1 - The function and architecture of DEAH/RHA helicases

AU - He, Yangzi

AU - Andersen, Gregers Rom

AU - Nielsen, Klaus Hvid

PY - 2012/7

Y1 - 2012/7

N2 - Helicases are ubiquitous enzymes that participate in every aspect of nucleic acid metabolism. The DEAH/RHA family of helicases are involved in a variety of cellular processes including transcriptional and translational regulation, pre-mRNA splicing, pre-rRNA processing, mRNA export and decay, in addition to the innate immune response. Recently, the first crystal structures of a DEAH/RHA helicase unveiled the unique structural features of this helicase family. These structures furthermore illuminate the molecular mechanism of these proteins and provide a framework for analysis of their interaction with nucleic acids, regulatory proteins and large macromolecular complexes.

AB - Helicases are ubiquitous enzymes that participate in every aspect of nucleic acid metabolism. The DEAH/RHA family of helicases are involved in a variety of cellular processes including transcriptional and translational regulation, pre-mRNA splicing, pre-rRNA processing, mRNA export and decay, in addition to the innate immune response. Recently, the first crystal structures of a DEAH/RHA helicase unveiled the unique structural features of this helicase family. These structures furthermore illuminate the molecular mechanism of these proteins and provide a framework for analysis of their interaction with nucleic acids, regulatory proteins and large macromolecular complexes.

U2 - 10.1515/bmc.2011.024

DO - 10.1515/bmc.2011.024

M3 - Review

C2 - 25962039

VL - 2

SP - 315

EP - 326

JO - BioMolecular Concepts

JF - BioMolecular Concepts

SN - 1868-5021

IS - 4

ER -