The comparative genomics and complex population history of Papio baboons

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DOI

  • Jeffrey Rogers, Baylor College of Medicine
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  • Muthuswamy Raveendran, Baylor College of Medicine
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  • R. Alan Harris, Baylor College of Medicine
  • ,
  • Thomas Mailund
  • Kalle Leppälä
  • Georgios Athanasiadis
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  • Mikkel Heide Schierup
  • Jade Cheng
  • Kasper Munch
  • Jerilyn A. Walker, Louisiana State University (LSU)
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  • Miriam K. Konkel, Clemson University
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  • Vallmer Jordan, Louisiana State University (LSU)
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  • Cody J. Steely, Louisiana State University (LSU)
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  • Thomas O. Beckstrom, Louisiana State University (LSU)
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  • Christina Bergey, New York University, The Pennsylvania State University
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  • Andrew Burrell, New York University
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  • Dominik Schrempf, Institut für Populationsgenetik, University of Veterinary Medicine
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  • Angela Noll, Leibniz Institute for Primate Research
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  • Maximillian Kothe, Leibniz Institute for Primate Research
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  • Gisela H. Kopp, Leibniz Institute for Primate Research, Fb. Physik der Univ. Konstanz, Max Planck Institute for Ornithology
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  • Yue Liu, Baylor College of Medicine
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  • Shwetha Murali, Baylor College of Medicine, University of Washington, Seattle
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  • Konstantinos Billis, European Bioinformatics Institute
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  • Fergal J. Martin, European Bioinformatics Institute
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  • Matthieu Muffato, European Bioinformatics Institute
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  • Laura Cox, Southwest National Primate Research Center, Wake Forest School of Medicine
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  • James Else, Emory University
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  • Todd Disotell, New York University
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  • Donna M. Muzny, Baylor College of Medicine
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  • Jane Phillips-Conroy, Internal Medicine, Washington University in St. Louis, School of Medicine, Washington University in St. Louis
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  • Bronwen Aken, European Bioinformatics Institute
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  • Evan E. Eichler, University of Washington, Seattle
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  • Tomas Marques-Bonet, PRBB, Theoretical and Computational Neuroscience Group, Center of Brain and Cognition, Universitat Pompeu Fabra, 08018 Barcelona, Spain; Institució Catalana de Recerca i Estudis Avançats (ICREA), 08010 Barcelona, Spain., Barcelona Institute of Science and Technology, Universitat Autònoma de Barcelona
  • ,
  • Carolin Kosiol, University of Veterinary Medicine, University of St. Andrews
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  • Mark A. Batzer, Louisiana State University (LSU)
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  • Matthew W. Hahn, Indiana University
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  • Jenny Tung, Duke University, Institute of Primate Research
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  • Dietmar Zinner, Leibniz Institute for Primate Research
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  • Christian Roos, Leibniz Institute for Primate Research
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  • Clifford J. Jolly, New York University
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  • Richard A. Gibbs, Baylor College of Medicine
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  • Kim C. Worley, Baylor College of Medicine
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  • Baboon Genome Analysis Consortium

Recent studies suggest that closely related species can accumulate substantial genetic and phenotypic differences despite ongoing gene flow, thus challenging traditional ideas regarding the genetics of speciation. Baboons (genus Papio) are Old World monkeys consisting of six readily distinguishable species. Baboon species hybridize in the wild, and prior data imply a complex history of differentiation and introgression. We produced a reference genome assembly for the olive baboon (Papio anubis) and whole-genome sequence data for all six extant species. We document multiple episodes of admixture and introgression during the radiation of Papio baboons, thus demonstrating their value as a model of complex evolutionary divergence, hybridization, and reticulation. These results help inform our understanding of similar cases, including modern humans, Neanderthals, Denisovans, and other ancient hominins.

Original languageEnglish
Article number6947
JournalScience Advances
Volume5
Issue1
Number of pages14
ISSN2375-2548
DOIs
Publication statusPublished - 30 Jan 2019

    Research areas

  • ANUBIS, CONCORDANCE, EVOLUTIONARY, GENETICS, HAMADRYAS, HYBRID ZONE, HYBRIDIZATION PATTERNS, PHYLOGENY, PHYLOGEOGRAPHY, TREE

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