The chemistry of 1,1-dithiolates: II. Formation of Thieno-1,2,3-triazines by diazotation of3-amino-thiophene-2 and 4-carboxamide

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  • L. Henriksen, Denmark
  • Herman Autrup, University of Copenhagen, Denmark
  • Institute of Environmental and Occupational Medicine
A series of thieno[3,2-e]-3,4-dihydro-1,2,3-triazin-4-ones (V) and thieno[3,4-e]-3,4-dihydro-1,2,3-triazin-4-ones (VI) were prepared by diazotation of 3-aminothiophene-2-carboxamides (III) and 4-amino-thiophene-3-carboxamides (IV), respectively, both obtained by cyclization of 2-cyanoethylene-1,1-dithiolates with α-halogenocarbonyl compounds. Characteristic differences between the two systems were found in the position of the long-wavelength UV absorption maximum and the acidity of the triazine ring proton. The latter property was reflected in the 1H NMR signal from this proton.
Original languageEnglish
JournalActa Chemica Scandinavica
Pages (from-to)3342-3346
Number of pages5
Publication statusPublished - 1972

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