TY - JOUR
T1 - Synthetic developments on the preparation of sulfides from thiol-free reagents
AU - Batista, Gabriel M.F.
AU - De Castro, Pedro P.
AU - Dos Santos, Juliana A.
AU - Skrydstrup, Troels
AU - Amarante, Giovanni W.
N1 - Funding Information:
We are grateful for generous financial support from CAPES (Finance Code 001), CNPq (310514/2018-5), FAPEMIG, and Rede Mineira de Química.
Publisher Copyright:
© 2021 the Partner Organisations.
Copyright:
Copyright 2021 Elsevier B.V., All rights reserved.
PY - 2021/1
Y1 - 2021/1
N2 - Thiols are known for their strong odor and high toxicity, which makes the development of thiol-free alternatives for the construction of sulfur-containing derivatives, in particular sulfides (thioethers), highly desirable. Over the last few years, several approaches for the preparation of these compounds from alternative sources, such as DMSO, disulfides, elemental sulfur, Bunte salts, and N-substituted sulfanylsuccinimides, have been described. This critical review presents an in-depth analysis of the preparation of these derivatives, including the presentation of selected examples and the careful discussion of mechanistic pathways.
AB - Thiols are known for their strong odor and high toxicity, which makes the development of thiol-free alternatives for the construction of sulfur-containing derivatives, in particular sulfides (thioethers), highly desirable. Over the last few years, several approaches for the preparation of these compounds from alternative sources, such as DMSO, disulfides, elemental sulfur, Bunte salts, and N-substituted sulfanylsuccinimides, have been described. This critical review presents an in-depth analysis of the preparation of these derivatives, including the presentation of selected examples and the careful discussion of mechanistic pathways.
UR - http://www.scopus.com/inward/record.url?scp=85100302230&partnerID=8YFLogxK
U2 - 10.1039/d0qo01226b
DO - 10.1039/d0qo01226b
M3 - Review
AN - SCOPUS:85100302230
SN - 2052-4129
VL - 8
SP - 326
EP - 368
JO - Organic Chemistry Frontiers
JF - Organic Chemistry Frontiers
IS - 2
ER -