Sustainable weight loss over three years in children with obesity: a pragmatic family-centered lifestyle intervention

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Sustainable weight loss over three years in children with obesity : a pragmatic family-centered lifestyle intervention. / Jørgensen, Rasmus Møller; Bruun, Jens Meldgaard; Kremke, Britta; Bahnsen, Rikke Frederiksen; Nielsen, Bent Windelborg; Vestergaard, Esben Thyssen.

In: Eating and Weight Disorders, Vol. 26, No. 2, 03.2021, p. 537-545.

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@article{68306282cd3140bca162e2b56c2775de,
title = "Sustainable weight loss over three years in children with obesity: a pragmatic family-centered lifestyle intervention",
abstract = "Introduction: Childhood obesity has psychological consequences and increases the risk of continuous obesity into adulthood, associated with development of non-communicable disease (e.g. type 2 diabetes). Short-term weight loss intervention studies show good results but long-term studies are limited. Methods: One hundred ninety-nine obese children (4–18 years of age), with a BMI-SDS (standard deviation score) above + 2 SDS were enrolled into a multifactorial family-centered lifestyle intervention study. The children had yearly visits in the outpatient clinic for anthropometrics, blood samples and DXA-scans, and 6–8 meeting with community health workers between these visits. The children followed the intervention up to 3 years. Results: After a follow-up of 26.7 ± 17.5 months a reduction in BMI-SDS of − 0.25 SDS (p < 0.001) was observed. The 57 children who were adherent to the intervention for ≥ 2 years had significantly reduced BMI-SDS compared to the 142 children with shorter intervention (BMI-SDS: − 0.38 ± 0.67 vs. − 0.20 ± 0.50, p = 0.036). All weight loss was accompanied by decrease in fat mass and increase in muscle mass (p < 0.001). Conclusion: The intervention was found to induce long-term reduction in BMI-SDS in obese children, with beneficial change in body composition. Children who followed the intervention the longest had the greatest reduction in BMI-SDS. Level of evidence: Level III, longitudinal cohort study.",
keywords = "Body composition, Children, Lifestyle intervention, Long-term, Obesity, Weight loss",
author = "J{\o}rgensen, {Rasmus M{\o}ller} and Bruun, {Jens Meldgaard} and Britta Kremke and Bahnsen, {Rikke Frederiksen} and Nielsen, {Bent Windelborg} and Vestergaard, {Esben Thyssen}",
year = "2021",
month = mar,
doi = "10.1007/s40519-020-00887-7",
language = "English",
volume = "26",
pages = "537--545",
journal = "Eating and Weight Disorders",
issn = "1124-4909",
publisher = "Italian Society for the Study of Eating Disorders",
number = "2",

}

RIS

TY - JOUR

T1 - Sustainable weight loss over three years in children with obesity

T2 - a pragmatic family-centered lifestyle intervention

AU - Jørgensen, Rasmus Møller

AU - Bruun, Jens Meldgaard

AU - Kremke, Britta

AU - Bahnsen, Rikke Frederiksen

AU - Nielsen, Bent Windelborg

AU - Vestergaard, Esben Thyssen

PY - 2021/3

Y1 - 2021/3

N2 - Introduction: Childhood obesity has psychological consequences and increases the risk of continuous obesity into adulthood, associated with development of non-communicable disease (e.g. type 2 diabetes). Short-term weight loss intervention studies show good results but long-term studies are limited. Methods: One hundred ninety-nine obese children (4–18 years of age), with a BMI-SDS (standard deviation score) above + 2 SDS were enrolled into a multifactorial family-centered lifestyle intervention study. The children had yearly visits in the outpatient clinic for anthropometrics, blood samples and DXA-scans, and 6–8 meeting with community health workers between these visits. The children followed the intervention up to 3 years. Results: After a follow-up of 26.7 ± 17.5 months a reduction in BMI-SDS of − 0.25 SDS (p < 0.001) was observed. The 57 children who were adherent to the intervention for ≥ 2 years had significantly reduced BMI-SDS compared to the 142 children with shorter intervention (BMI-SDS: − 0.38 ± 0.67 vs. − 0.20 ± 0.50, p = 0.036). All weight loss was accompanied by decrease in fat mass and increase in muscle mass (p < 0.001). Conclusion: The intervention was found to induce long-term reduction in BMI-SDS in obese children, with beneficial change in body composition. Children who followed the intervention the longest had the greatest reduction in BMI-SDS. Level of evidence: Level III, longitudinal cohort study.

AB - Introduction: Childhood obesity has psychological consequences and increases the risk of continuous obesity into adulthood, associated with development of non-communicable disease (e.g. type 2 diabetes). Short-term weight loss intervention studies show good results but long-term studies are limited. Methods: One hundred ninety-nine obese children (4–18 years of age), with a BMI-SDS (standard deviation score) above + 2 SDS were enrolled into a multifactorial family-centered lifestyle intervention study. The children had yearly visits in the outpatient clinic for anthropometrics, blood samples and DXA-scans, and 6–8 meeting with community health workers between these visits. The children followed the intervention up to 3 years. Results: After a follow-up of 26.7 ± 17.5 months a reduction in BMI-SDS of − 0.25 SDS (p < 0.001) was observed. The 57 children who were adherent to the intervention for ≥ 2 years had significantly reduced BMI-SDS compared to the 142 children with shorter intervention (BMI-SDS: − 0.38 ± 0.67 vs. − 0.20 ± 0.50, p = 0.036). All weight loss was accompanied by decrease in fat mass and increase in muscle mass (p < 0.001). Conclusion: The intervention was found to induce long-term reduction in BMI-SDS in obese children, with beneficial change in body composition. Children who followed the intervention the longest had the greatest reduction in BMI-SDS. Level of evidence: Level III, longitudinal cohort study.

KW - Body composition

KW - Children

KW - Lifestyle intervention

KW - Long-term

KW - Obesity

KW - Weight loss

UR - http://www.scopus.com/inward/record.url?scp=85082715196&partnerID=8YFLogxK

U2 - 10.1007/s40519-020-00887-7

DO - 10.1007/s40519-020-00887-7

M3 - Journal article

C2 - 32170662

AN - SCOPUS:85082715196

VL - 26

SP - 537

EP - 545

JO - Eating and Weight Disorders

JF - Eating and Weight Disorders

SN - 1124-4909

IS - 2

ER -