Subpopulations and Cognitive Behavioral Therapy Outcome in The Nordic Long-Term OCD Treatment Study (NordLOTS)

David R.M.A. Højgaard, Tord Ivarsson, Bernhard Weidle, Karin Melin, Sanne Jensen, Nor Christian Torp, Gudmundur Skarphedinsson, Katja Anna Hybel, Judith Becker Nissen, Kitty Dahl, Robert Valderhaug, Charlotte Steen Duholm, Orri Smárason, Trine Wigh Arildskov, Þórhildur Ólafsdóttir, Charlotte Ulrikka Rask, Per Hove Thomsen

Research output: Contribution to conferenceConference abstract for conferenceResearch

Abstract

Objectives

The aim was to describe sub-populations and examine cognitive-behavioral therapy (CBT) outcome from the Nordic Long-Term OCD Treatment Study (NordLOTS), based on health anxiety symptoms (HAS), body dysmorphic symptoms (BDS), tic symptoms (TS), hoarding symptoms (HS), autism spectrum disorder symptoms (ASDS), age and OCD symptom type.

Methods

The NordLOTS included 269 OCD patients aged 7-17 years with OCD (DSM-IV) who all received stepped-care treatment beginning with 14 weekly sessions of CBT and assessed 3 years after ended treatment.

Results

HAS were present in 31% of the participants (often with other anxiety symptoms), BDS in 7.8% of the sample and correlated with age and other anxiety symptoms, ASDS symptoms in 10% with higher rates of ADHD and tic disorders, lower insight, more indecisiveness and pervasive slowness. TS were found in 29.9% of participants, who were more likely to be male, have earlier OCD onset, more impairment and comorbidity. HS were seen in 26.8%, who also had more comorbid tic disorders and indecision. All subgroups (including age groups) presented with different OCD symptom profiles. Patients with higher levels of symmetry/hoarding related symptoms responded slightly more favorable to CBT than those with other types of OCD symptoms. Contamination symptoms may be important for a specific population of limited responders.

Conclusions

Although subpopulations presented with different demographic and clinical profiles, most did not differ in their response to CBT. Symmetry/hoarding related OCD may show a slightly more favorable response to CBT compared with other types of OCD.
Original languageEnglish
Publication date1 Jul 2023
Publication statusPublished - 1 Jul 2023
Event20th International Congress of the European Society for Child and Adolescent Psychiatry - Copenhagen, Denmark
Duration: 29 Jun 20231 Jul 2023
Conference number: 20
https://www.escap2023.eu/

Conference

Conference20th International Congress of the European Society for Child and Adolescent Psychiatry
Number20
Country/TerritoryDenmark
CityCopenhagen
Period29/06/202301/07/2023
Internet address

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