SUBMERGED PERFUSION BIOREACTOR: Biological device for, e.g. cell culturing, has body delimited by rim comprising recessed portion that is cavity in rim of body, and wall delimiting recessed portion comprising outlet orifice allowing liquid medium to flow out of body

Dang Quang Svend Le; Morten Foss; Jens Vinge Nygaard; Cody Bünger; Flemming Besenbacher

SUBMERGED PERFUSION BIOREACTOR: Biological device for, e.g. cell culturing, has body delimited by rim comprising recessed portion that is cavity in rim of body, and wall delimiting recessed portion comprising outlet orifice allowing liquid medium to flow out of body

Dang Quang Svend Le (Inventor), Morten Foss (Inventor), Jens Vinge Nygaard (Inventor), Cody Bünger (Inventor), Flemming Besenbacher (Inventor)

Research output: Patent

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Abstract

NOVELTY - A biological device comprises a body (1) delimited by a rim (7) comprising recessed portion(s) that is a cavity in the rim of the body, and a first wall delimiting the recessed portion along the cavity. The recessed portion(s) comprise a first outlet orifice allowing the liquid medium to flow out of the body.

USE - A biological device for cell culturing, enzymatic reactions or filtering of fluid (claimed).

ADVANTAGE - The device has simple setup without the need of external pumping mechanisms to obtain a perfusion flow system.

DETAILED DESCRIPTION - A biological device comprises a body (1) delimited by a rim (7), and having a first and a second surface defining a body thickness; an aperture (3) in the center of the body, and is covered at the first and second surface by a first and second plate comprising an inlet orifice allowing liquid medium into the aperture; mechanism for rotating arranged in the aperture between the first and second plate; and outlet channel(s) connecting the aperture with the recessed portion. The rim comprises recessed portion(s) that is a cavity in the rim of the body, and a first wall delimiting the recessed portion along the cavity. The recessed portion(s) comprise a first outlet orifice allowing the liquid medium to flow out of the body. An INDEPENDENT CLAIM is included for a method of using a device for biological purposes.

Translated title of the contribution	Nedsænket perfusionsbioreaktor
Original language	English
IPC	C12M 1/10 (2006.01)
Patent number	WO/2010/139337
Filing date	09/12/2010
Country/Territory	Denmark
Publication status	Published - 9 Dec 2010

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Le, D. Q. S., Foss, M., Nygaard, J. V., Bünger, C., & Besenbacher, F. (2010). SUBMERGED PERFUSION BIOREACTOR: Biological device for, e.g. cell culturing, has body delimited by rim comprising recessed portion that is cavity in rim of body, and wall delimiting recessed portion comprising outlet orifice allowing liquid medium to flow out of body. (Patent No. WO/2010/139337).

Le, Dang Quang Svend (Inventor) ; Foss, Morten (Inventor) ; Nygaard, Jens Vinge (Inventor) et al. / SUBMERGED PERFUSION BIOREACTOR : Biological device for, e.g. cell culturing, has body delimited by rim comprising recessed portion that is cavity in rim of body, and wall delimiting recessed portion comprising outlet orifice allowing liquid medium to flow out of body. Patent No.: WO/2010/139337. Dec 09, 2010.

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title = "SUBMERGED PERFUSION BIOREACTOR: Biological device for, e.g. cell culturing, has body delimited by rim comprising recessed portion that is cavity in rim of body, and wall delimiting recessed portion comprising outlet orifice allowing liquid medium to flow out of body",

abstract = "NOVELTY - A biological device comprises a body (1) delimited by a rim (7) comprising recessed portion(s) that is a cavity in the rim of the body, and a first wall delimiting the recessed portion along the cavity. The recessed portion(s) comprise a first outlet orifice allowing the liquid medium to flow out of the body.USE - A biological device for cell culturing, enzymatic reactions or filtering of fluid (claimed).ADVANTAGE - The device has simple setup without the need of external pumping mechanisms to obtain a perfusion flow system.DETAILED DESCRIPTION - A biological device comprises a body (1) delimited by a rim (7), and having a first and a second surface defining a body thickness; an aperture (3) in the center of the body, and is covered at the first and second surface by a first and second plate comprising an inlet orifice allowing liquid medium into the aperture; mechanism for rotating arranged in the aperture between the first and second plate; and outlet channel(s) connecting the aperture with the recessed portion. The rim comprises recessed portion(s) that is a cavity in the rim of the body, and a first wall delimiting the recessed portion along the cavity. The recessed portion(s) comprise a first outlet orifice allowing the liquid medium to flow out of the body. An INDEPENDENT CLAIM is included for a method of using a device for biological purposes.",

keywords = "Bioreactor, Stem Cell Transplantation, scaffold, Tissue Engineering, Drug Evaluation",

author = "Le, {Dang Quang Svend} and Morten Foss and Nygaard, {Jens Vinge} and Cody B{\"u}nger and Flemming Besenbacher",

year = "2010",

month = dec,

day = "9",

language = "English",

type = "Patent",

note = " WO/2010/139337; C12M 1/10 (2006.01)",

}

SUBMERGED PERFUSION BIOREACTOR: Biological device for, e.g. cell culturing, has body delimited by rim comprising recessed portion that is cavity in rim of body, and wall delimiting recessed portion comprising outlet orifice allowing liquid medium to flow out of body. / Le, Dang Quang Svend (Inventor); Foss, Morten (Inventor); Nygaard, Jens Vinge (Inventor) et al.
Patent No.: WO/2010/139337. Dec 09, 2010.

Research output: Patent

TY - PAT

T1 - SUBMERGED PERFUSION BIOREACTOR

T2 - Biological device for, e.g. cell culturing, has body delimited by rim comprising recessed portion that is cavity in rim of body, and wall delimiting recessed portion comprising outlet orifice allowing liquid medium to flow out of body

AU - Le, Dang Quang Svend

AU - Foss, Morten

AU - Nygaard, Jens Vinge

AU - Bünger, Cody

AU - Besenbacher, Flemming

PY - 2010/12/9

Y1 - 2010/12/9

N2 - NOVELTY - A biological device comprises a body (1) delimited by a rim (7) comprising recessed portion(s) that is a cavity in the rim of the body, and a first wall delimiting the recessed portion along the cavity. The recessed portion(s) comprise a first outlet orifice allowing the liquid medium to flow out of the body.USE - A biological device for cell culturing, enzymatic reactions or filtering of fluid (claimed).ADVANTAGE - The device has simple setup without the need of external pumping mechanisms to obtain a perfusion flow system.DETAILED DESCRIPTION - A biological device comprises a body (1) delimited by a rim (7), and having a first and a second surface defining a body thickness; an aperture (3) in the center of the body, and is covered at the first and second surface by a first and second plate comprising an inlet orifice allowing liquid medium into the aperture; mechanism for rotating arranged in the aperture between the first and second plate; and outlet channel(s) connecting the aperture with the recessed portion. The rim comprises recessed portion(s) that is a cavity in the rim of the body, and a first wall delimiting the recessed portion along the cavity. The recessed portion(s) comprise a first outlet orifice allowing the liquid medium to flow out of the body. An INDEPENDENT CLAIM is included for a method of using a device for biological purposes.

AB - NOVELTY - A biological device comprises a body (1) delimited by a rim (7) comprising recessed portion(s) that is a cavity in the rim of the body, and a first wall delimiting the recessed portion along the cavity. The recessed portion(s) comprise a first outlet orifice allowing the liquid medium to flow out of the body.USE - A biological device for cell culturing, enzymatic reactions or filtering of fluid (claimed).ADVANTAGE - The device has simple setup without the need of external pumping mechanisms to obtain a perfusion flow system.DETAILED DESCRIPTION - A biological device comprises a body (1) delimited by a rim (7), and having a first and a second surface defining a body thickness; an aperture (3) in the center of the body, and is covered at the first and second surface by a first and second plate comprising an inlet orifice allowing liquid medium into the aperture; mechanism for rotating arranged in the aperture between the first and second plate; and outlet channel(s) connecting the aperture with the recessed portion. The rim comprises recessed portion(s) that is a cavity in the rim of the body, and a first wall delimiting the recessed portion along the cavity. The recessed portion(s) comprise a first outlet orifice allowing the liquid medium to flow out of the body. An INDEPENDENT CLAIM is included for a method of using a device for biological purposes.

KW - Bioreactor

KW - Stem Cell Transplantation

KW - scaffold

KW - Tissue Engineering

KW - Drug Evaluation

M3 - Patent

M1 - WO/2010/139337

Y2 - 2010/12/09

ER -