NOVELTY - A biological device comprises a body (1) delimited by a rim (7) comprising recessed portion(s) that is a cavity in the rim of the body, and a first wall delimiting the recessed portion along the cavity. The recessed portion(s) comprise a first outlet orifice allowing the liquid medium to flow out of the body.

USE - A biological device for cell culturing, enzymatic reactions or filtering of fluid (claimed).

ADVANTAGE - The device has simple setup without the need of external pumping mechanisms to obtain a perfusion flow system.

DETAILED DESCRIPTION - A biological device comprises a body (1) delimited by a rim (7), and having a first and a second surface defining a body thickness; an aperture (3) in the center of the body, and is covered at the first and second surface by a first and second plate comprising an inlet orifice allowing liquid medium into the aperture; mechanism for rotating arranged in the aperture between the first and second plate; and outlet channel(s) connecting the aperture with the recessed portion. The rim comprises recessed portion(s) that is a cavity in the rim of the body, and a first wall delimiting the recessed portion along the cavity. The recessed portion(s) comprise a first outlet orifice allowing the liquid medium to flow out of the body. An INDEPENDENT CLAIM is included for a method of using a device for biological purposes.