Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Stoppage in Autism Spectrum Disorders. / Grønborg, Therese Koops; Hansen, Stefan Nygaard; Nielsen, Svend et al.
In: Journal of Autism and Developmental Disorders, Vol. 45, No. 11, 11.2015, p. 3509-3519.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
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TY - JOUR
T1 - Stoppage in Autism Spectrum Disorders
AU - Grønborg, Therese Koops
AU - Hansen, Stefan Nygaard
AU - Nielsen, Svend
AU - Skytthe, Axel
AU - Parner, Erik T
PY - 2015/11
Y1 - 2015/11
N2 - Stoppage refers to changes in reproductive behavior following the birth of a child with a severe disease. The presence of stoppage can bias estimates of sibling recurrence risk if not properly addressed. If stoppage occurs non-randomly (differential stoppage), it is possibly an additional source of bias in sibling recurrence risk estimation. This study investigated whether stoppage occurs in Danish families with a firstborn child diagnosed with autism spectrum disorders, and if stoppage was differential. We found that stoppage occurs moderately in Danish families affected by autism spectrum disorders, and that stoppage is differential. However, differential stoppage is a minor source of estimation bias in Danish sibling recurrence risk studies of autism spectrum disorders.
AB - Stoppage refers to changes in reproductive behavior following the birth of a child with a severe disease. The presence of stoppage can bias estimates of sibling recurrence risk if not properly addressed. If stoppage occurs non-randomly (differential stoppage), it is possibly an additional source of bias in sibling recurrence risk estimation. This study investigated whether stoppage occurs in Danish families with a firstborn child diagnosed with autism spectrum disorders, and if stoppage was differential. We found that stoppage occurs moderately in Danish families affected by autism spectrum disorders, and that stoppage is differential. However, differential stoppage is a minor source of estimation bias in Danish sibling recurrence risk studies of autism spectrum disorders.
KW - autism spectrum disorder
KW - sibling recurrence risk
KW - stoppage
U2 - 10.1007/s10803-015-2497-3
DO - 10.1007/s10803-015-2497-3
M3 - Journal article
C2 - 26077953
VL - 45
SP - 3509
EP - 3519
JO - Journal of Autism and Developmental Disorders
JF - Journal of Autism and Developmental Disorders
SN - 0162-3257
IS - 11
ER -