Abstract
We show that kinetin, a non-natural product with strong cytokinin activity, is incorporated into prokaryotic and eukaryotic tRNAs in the exchange reaction catalysed by a putative tRNA-kinetin transglycosylase. We also show that kinetin is specifically incorporated into E. coli tRNA(Tyr) and most probably at position 37. To our knowledge, this is the first report of a nucleic acid base exchange reaction occurring at this position.
Original language | English |
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Journal | Biochemistry international |
Volume | 28 |
Issue | 5 |
Pages (from-to) | 805-811 |
Number of pages | 7 |
ISSN | 0158-5231 |
Publication status | Published - 1 Dec 1992 |