Sodium retention by uPA-plasmin-ENaC in nephrotic syndrome: Authors reply

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperEditorialResearchpeer-review

DOI

  • Gitte Rye Hinrichs, Department of Cardiovascular and Renal Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.
  • ,
  • Kathrin Weyer
  • Ulla G Friis, Department of Cardiovascular and Renal Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.
  • ,
  • Per Svenningsen, Department of Cardiovascular and Renal Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.
  • ,
  • Ida Katrine Lund, Biotech Research and Innovation Centre (BRIC), University of Copenhagen, Copenhagen, Denmark.
  • ,
  • Rikke Nielsen
  • Géraldine Mollet, Inserm U1163, Imagine Institute, Laboratory of Hereditary Kidney Diseases, Paris, France; Paris Descartes-Sorbonne Paris Cité University, Paris, France.
  • ,
  • Corinne Antignac, Inserm U1163, Imagine Institute, Laboratory of Hereditary Kidney Diseases, Paris, France; Paris Descartes-Sorbonne Paris Cité University, Paris, France; Department of Genetics, Necker Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.
  • ,
  • Claus Bistrup, Department of Oncology, Odense University Hospital, Denmark; Department of Clinical Research, University of Southern Denmark, Odense C, Denmark; OPEN, Odense Patient Data Explorative Network, Department of Clinical Research, University of Southern Denmark, Odense C, Denmark. Electronic address: Julie.Killerup.Kaae@rsyd.dk.
  • ,
  • Boye L Jensen, Department of Cardiovascular and Renal Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.
  • ,
  • Henrik Birn

There is a great interest in exploring the mechanisms of oedema in nephrotic syndrome (NS) as evidenced by 2 parallel studies published in Acta Physiologica (1, 2). This has generated an editorial comment (3) which we respond to by this rebuttal. The interest in the nephrotic edema reflects not only the significant negative impact this has on the quality of life, but also the difficulties associated with identifying optimal treatment due to the lack of pathophysiological insight.

Original languageEnglish
Article numbere13432
JournalActa Physiologica (Print)
Volume228
Issue4
ISSN1748-1708
DOIs
Publication statusPublished - 2020

See relations at Aarhus University Citationformats

ID: 174394886