Silylcarboxylic Acids as Bifunctional Reagents: Application in Palladium-Catalyzed External-CO-Free Carbonylative Cross-Coupling Reactions

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

Standard

Silylcarboxylic Acids as Bifunctional Reagents : Application in Palladium-Catalyzed External-CO-Free Carbonylative Cross-Coupling Reactions. / Li, Xiong; Xu, Jie; Li, Yue; Kramer, Søren; Skrydstrup, Troels; Lian, Zhong.

In: Advanced Synthesis and Catalysis, Vol. 362, No. 19, 10.2020, p. 4078-4083.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

Harvard

APA

CBE

MLA

Vancouver

Author

Li, Xiong ; Xu, Jie ; Li, Yue ; Kramer, Søren ; Skrydstrup, Troels ; Lian, Zhong. / Silylcarboxylic Acids as Bifunctional Reagents : Application in Palladium-Catalyzed External-CO-Free Carbonylative Cross-Coupling Reactions. In: Advanced Synthesis and Catalysis. 2020 ; Vol. 362, No. 19. pp. 4078-4083.

Bibtex

@article{da956eec3e0f4247a1eee00980472892,
title = "Silylcarboxylic Acids as Bifunctional Reagents: Application in Palladium-Catalyzed External-CO-Free Carbonylative Cross-Coupling Reactions",
abstract = "A palladium-catalyzed external-CO-free carbonylative Hiyama-Denmark cross-coupling reaction is presented. The introduction of silylcarboxylic acids as bifunctional reagents (CO and nucleophile source) avoids the need for external gaseous CO and a silylarene coupling partner. The transformation features high functional group tolerance and it is successful with electron-rich, -neutral, and -poor aryl iodides. Stoichiometric studies and control experiments provide insight into the reaction mechanism and support the hypothesized dual role of silylcarboxylic acids. (Figure presented.).",
keywords = "Carbonylation, Cross-coupling, Hiyama-Denmark, Palladium-catalysis",
author = "Xiong Li and Jie Xu and Yue Li and S{\o}ren Kramer and Troels Skrydstrup and Zhong Lian",
year = "2020",
month = oct,
doi = "10.1002/adsc.202000586",
language = "English",
volume = "362",
pages = "4078--4083",
journal = "Advanced Synthesis & Catalysis",
issn = "1615-4150",
publisher = "Wiley - V C H Verlag GmbH & Co. KGaA",
number = "19",

}

RIS

TY - JOUR

T1 - Silylcarboxylic Acids as Bifunctional Reagents

T2 - Application in Palladium-Catalyzed External-CO-Free Carbonylative Cross-Coupling Reactions

AU - Li, Xiong

AU - Xu, Jie

AU - Li, Yue

AU - Kramer, Søren

AU - Skrydstrup, Troels

AU - Lian, Zhong

PY - 2020/10

Y1 - 2020/10

N2 - A palladium-catalyzed external-CO-free carbonylative Hiyama-Denmark cross-coupling reaction is presented. The introduction of silylcarboxylic acids as bifunctional reagents (CO and nucleophile source) avoids the need for external gaseous CO and a silylarene coupling partner. The transformation features high functional group tolerance and it is successful with electron-rich, -neutral, and -poor aryl iodides. Stoichiometric studies and control experiments provide insight into the reaction mechanism and support the hypothesized dual role of silylcarboxylic acids. (Figure presented.).

AB - A palladium-catalyzed external-CO-free carbonylative Hiyama-Denmark cross-coupling reaction is presented. The introduction of silylcarboxylic acids as bifunctional reagents (CO and nucleophile source) avoids the need for external gaseous CO and a silylarene coupling partner. The transformation features high functional group tolerance and it is successful with electron-rich, -neutral, and -poor aryl iodides. Stoichiometric studies and control experiments provide insight into the reaction mechanism and support the hypothesized dual role of silylcarboxylic acids. (Figure presented.).

KW - Carbonylation

KW - Cross-coupling

KW - Hiyama-Denmark

KW - Palladium-catalysis

UR - http://www.scopus.com/inward/record.url?scp=85088524560&partnerID=8YFLogxK

U2 - 10.1002/adsc.202000586

DO - 10.1002/adsc.202000586

M3 - Journal article

AN - SCOPUS:85088524560

VL - 362

SP - 4078

EP - 4083

JO - Advanced Synthesis & Catalysis

JF - Advanced Synthesis & Catalysis

SN - 1615-4150

IS - 19

ER -