Department of Economics and Business Economics

Short-term effectiveness of medication and psychosocial intervention in a cohort of newly diagnosed patients with inattention, impulsivity, and hyperactivity problems

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  • Bruno Falissard, Institut National de la Santé et de la Recherche Médicale, Paris Descartes University, Hopital Paul-Brousse
  • ,
  • David Coghill, University of Dundee
  • ,
  • Aribert Rothenberger, University of Göttingen
  • ,
  • Maria Lorenzo, Eli Lilly and Company
  • ,
  • ADORE study group

Objective: The article discusses the ADHD Observational Research in Europe (ADORE) study that examined the impact of early treatment choices on outcome within the first few months, in previously untreated children with impairing inattention, impulsivity, and hyperactivity. Methods: Data are collected from a longitudinal, observational study conducted in 10 European countries that involve 1,478 children (aged 6 to 18 years) with symptoms of hyperactivity, impulsivity, or inattentiveness. Linear model with a propensity score adjustment compares the decrease in ADHD-RS scores between baseline and last recorded visit across treatment groups (2 to 5 months). Results: At baseline, 49.9% of participants are prescribed pharmacotherapy and 44.3% a psychosocial intervention. Analysis of the effect of treatment on the evolution of ADHD-RS scores shows a positive effect of medications and either an insignificant or negative effect of psychosocial intervention. Conclusions: Early use of medication effectively reduces ADHD symptoms in routine clinical practice in Europe. The effect of psychosocial intervention has to be interpreted cautiously because the number, length, and level of standard of the sessions are not taken into account in the analyses.

Original languageEnglish
JournalJournal of Attention Disorders
Pages (from-to)147-156
Number of pages10
Publication statusPublished - 2010

    Research areas

  • ADHD, cohort study, medication, psychosocial intervention, treatment evaluation

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