Sex differences in the genetic architecture of lifespan in a seed beetle: extreme inbreeding extends male lifespan

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Sex differences in the genetic architecture of lifespan in a seed beetle: extreme inbreeding extends male lifespan. / Bilde, T.; Maklakov, Alexei A.; Meisner, Katrine; la Guardia, Lucia; Friberg, Urban.

In: B M C Evolutionary Biology, Vol. 9, No. 33, 2009.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

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Bilde, T, Maklakov, AA, Meisner, K, la Guardia, L & Friberg, U 2009, 'Sex differences in the genetic architecture of lifespan in a seed beetle: extreme inbreeding extends male lifespan', B M C Evolutionary Biology, vol. 9, no. 33. https://doi.org/10.1186/1471-2148-9-33

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Bilde, T. ; Maklakov, Alexei A. ; Meisner, Katrine ; la Guardia, Lucia ; Friberg, Urban. / Sex differences in the genetic architecture of lifespan in a seed beetle: extreme inbreeding extends male lifespan. In: B M C Evolutionary Biology. 2009 ; Vol. 9, No. 33.

Bibtex

@article{36883e30aa8e11dea554000ea68e967b,
title = "Sex differences in the genetic architecture of lifespan in a seed beetle: extreme inbreeding extends male lifespan",
abstract = "BackgroundSex differences in lifespan are ubiquitous throughout the animal kingdom but the causes underlying this phenomenon remain poorly understood. Several explanations based on asymmetrical inheritance patterns (sex chromosomes or mitochondrial DNA) have been proposed, but these ideas have rarely been tested experimentally. Alternatively, sexual dimorphism in lifespan could result from sex-specific selection, caused by fundamental differences in how males and females optimize their fitness by allocating resources into current and future reproduction.ResultsHere we used sex-specific responses to inbreeding to study the genetic architecture of lifespan and mortality rates in Callosobruchus maculatus, a seed beetle that shows sexual dimorphism in lifespan. Two independent assays revealed opposing sex-specific responses to inbreeding. The combined data set showed that inbred males live longer than outbred males, while females show the opposite pattern. Both sexes suffered reduced fitness measured as lifetime reproductive success as a result of inbreeding.ConclusionNo model based on asymmetrical inheritance can explain increased male lifespan in response to inbreeding. Our results are however compatible with models based on sex-specific selection on reproductive strategies. We therefore suggest that sex-specific differences in lifespan in this species primarily result from sexually divergent selection.",
author = "T. Bilde and Maklakov, {Alexei A.} and Katrine Meisner and {la Guardia}, Lucia and Urban Friberg",
year = "2009",
doi = "10.1186/1471-2148-9-33",
language = "English",
volume = "9",
journal = "B M C Evolutionary Biology",
issn = "1471-2148",
publisher = "BioMed Central Ltd.",
number = "33",

}

RIS

TY - JOUR

T1 - Sex differences in the genetic architecture of lifespan in a seed beetle: extreme inbreeding extends male lifespan

AU - Bilde, T.

AU - Maklakov, Alexei A.

AU - Meisner, Katrine

AU - la Guardia, Lucia

AU - Friberg, Urban

PY - 2009

Y1 - 2009

N2 - BackgroundSex differences in lifespan are ubiquitous throughout the animal kingdom but the causes underlying this phenomenon remain poorly understood. Several explanations based on asymmetrical inheritance patterns (sex chromosomes or mitochondrial DNA) have been proposed, but these ideas have rarely been tested experimentally. Alternatively, sexual dimorphism in lifespan could result from sex-specific selection, caused by fundamental differences in how males and females optimize their fitness by allocating resources into current and future reproduction.ResultsHere we used sex-specific responses to inbreeding to study the genetic architecture of lifespan and mortality rates in Callosobruchus maculatus, a seed beetle that shows sexual dimorphism in lifespan. Two independent assays revealed opposing sex-specific responses to inbreeding. The combined data set showed that inbred males live longer than outbred males, while females show the opposite pattern. Both sexes suffered reduced fitness measured as lifetime reproductive success as a result of inbreeding.ConclusionNo model based on asymmetrical inheritance can explain increased male lifespan in response to inbreeding. Our results are however compatible with models based on sex-specific selection on reproductive strategies. We therefore suggest that sex-specific differences in lifespan in this species primarily result from sexually divergent selection.

AB - BackgroundSex differences in lifespan are ubiquitous throughout the animal kingdom but the causes underlying this phenomenon remain poorly understood. Several explanations based on asymmetrical inheritance patterns (sex chromosomes or mitochondrial DNA) have been proposed, but these ideas have rarely been tested experimentally. Alternatively, sexual dimorphism in lifespan could result from sex-specific selection, caused by fundamental differences in how males and females optimize their fitness by allocating resources into current and future reproduction.ResultsHere we used sex-specific responses to inbreeding to study the genetic architecture of lifespan and mortality rates in Callosobruchus maculatus, a seed beetle that shows sexual dimorphism in lifespan. Two independent assays revealed opposing sex-specific responses to inbreeding. The combined data set showed that inbred males live longer than outbred males, while females show the opposite pattern. Both sexes suffered reduced fitness measured as lifetime reproductive success as a result of inbreeding.ConclusionNo model based on asymmetrical inheritance can explain increased male lifespan in response to inbreeding. Our results are however compatible with models based on sex-specific selection on reproductive strategies. We therefore suggest that sex-specific differences in lifespan in this species primarily result from sexually divergent selection.

U2 - 10.1186/1471-2148-9-33

DO - 10.1186/1471-2148-9-33

M3 - Journal article

C2 - 19200350

VL - 9

JO - B M C Evolutionary Biology

JF - B M C Evolutionary Biology

SN - 1471-2148

IS - 33

ER -