Serum levels of bioactive IGF1 and physiological markers of ageing in healthy adults

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Senescent changes in body composition and muscle strength are accompanied by reduced production of GH and IGF1, but the causal relationship remains elusive. We speculate that serum bioactive IGF1, measured by the IGF1 kinase receptor activation assay, is closer related to human physiological ageing than total IGF1 measured by immunoassay.
Original languageEnglish
JournalEuropean journal of endocrinology / European Federation of Endocrine Societies
Pages (from-to)229-36
Number of pages8
Publication statusPublished - 2013

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