Serie: Medicamenten en mondzorg. Systematisch literatuuronderzoek naar effect van medicatie op de speekselklieren

Andy Wolff; Revan Kumar Joshi; Jörgen Ekström; Doron Aframian; Anne Marie Lynge Pedersen; Gordon Proctor; Nagamani Narayana; Alessandro Villa; Ying Wai Sia; Ardita Aliko; Richard McGowan; Alexander Ross Kerr; Siri Beier Jensen; Arjan Vissink; Colin Dawes

doi:10.5177/ntvt.2018.11.18203

Serie: Medicamenten en mondzorg. Systematisch literatuuronderzoek naar effect van medicatie op de speekselklieren

Andy Wolff, Revan Kumar Joshi, Jörgen Ekström, Doron Aframian, Anne Marie Lynge Pedersen, Gordon Proctor, Nagamani Narayana, Alessandro Villa, Ying Wai Sia, Ardita Aliko, Richard McGowan, Alexander Ross Kerr, Siri Beier Jensen, Arjan Vissink, Colin Dawes

Department of Dentistry and Oral Health

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Communication

Abstract

Evidence-based reviews of drugs causing medication-induced salivary gland dysfunction, such as xerostomia (sensation of oral dryness) and subjective sialorrhea are lacking. To compile a list of medicaments that influence salivary gland function, electronic databases were searched for relevant articles published up to June 2013. A total of 269 papers out of 3,867 records located satisfied the inclusion criteria (relevance, quality of methodology, strength of evidence). A total of 56 active substances with a higher level of evidence and 50 active substances with a moderate level of evidence of causing salivary gland dysfunction are described in this article. While xerostomia was a commonly reported outcome, the objective effect on salivary secretion was rarely measured. Xerostomia was, moreover, mostly reported as a negative side effect instead of the intended effect of that drug. A comprehensive list of medications having documented effects on salivary gland function or symptoms was compiled, which may assist practitioners in assessing patients who complain of dry mouth while taking medications.

Original language	Dutch
Journal	Nederlands Tijdschrift voor Tandheelkunde
Volume	125
Pages (from-to)	593-601
Number of pages	9
ISSN	0028-2200
DOIs	https://doi.org/10.5177/ntvt.2018.11.18203
Publication status	Published - 2018

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10.5177/ntvt.2018.11.18203

Cite this

Wolff, A., Joshi, R. K., Ekström, J., Aframian, D., Pedersen, A. M. L., Proctor, G., Narayana, N., Villa, A., Sia, Y. W., Aliko, A., McGowan, R., Kerr, A. R., Jensen, S. B., Vissink, A., & Dawes, C. (2018). Serie: Medicamenten en mondzorg. Systematisch literatuuronderzoek naar effect van medicatie op de speekselklieren. Nederlands Tijdschrift voor Tandheelkunde, 125, 593-601. https://doi.org/10.5177/ntvt.2018.11.18203

@article{686d1d7d12244cbeabfb1b97468988de,

title = "Serie: Medicamenten en mondzorg. Systematisch literatuuronderzoek naar effect van medicatie op de speekselklieren",

abstract = "Evidence-based reviews of drugs causing medication-induced salivary gland dysfunction, such as xerostomia (sensation of oral dryness) and subjective sialorrhea are lacking. To compile a list of medicaments that influence salivary gland function, electronic databases were searched for relevant articles published up to June 2013. A total of 269 papers out of 3,867 records located satisfied the inclusion criteria (relevance, quality of methodology, strength of evidence). A total of 56 active substances with a higher level of evidence and 50 active substances with a moderate level of evidence of causing salivary gland dysfunction are described in this article. While xerostomia was a commonly reported outcome, the objective effect on salivary secretion was rarely measured. Xerostomia was, moreover, mostly reported as a negative side effect instead of the intended effect of that drug. A comprehensive list of medications having documented effects on salivary gland function or symptoms was compiled, which may assist practitioners in assessing patients who complain of dry mouth while taking medications.",

author = "Andy Wolff and Joshi, {Revan Kumar} and J{\"o}rgen Ekstr{\"o}m and Doron Aframian and Pedersen, {Anne Marie Lynge} and Gordon Proctor and Nagamani Narayana and Alessandro Villa and Sia, {Ying Wai} and Ardita Aliko and Richard McGowan and Kerr, {Alexander Ross} and Jensen, {Siri Beier} and Arjan Vissink and Colin Dawes",

year = "2018",

doi = "10.5177/ntvt.2018.11.18203",

language = "Nederlandsk",

volume = "125",

pages = "593--601",

journal = "Nederlands Tijdschrift voor Tandheelkunde",

issn = "0028-2200",

publisher = "G J D Tholen N V",

}

Wolff, A, Joshi, RK, Ekström, J, Aframian, D, Pedersen, AML, Proctor, G, Narayana, N, Villa, A, Sia, YW, Aliko, A, McGowan, R, Kerr, AR, Jensen, SB, Vissink, A & Dawes, C 2018, 'Serie: Medicamenten en mondzorg. Systematisch literatuuronderzoek naar effect van medicatie op de speekselklieren', Nederlands Tijdschrift voor Tandheelkunde, vol. 125, pp. 593-601. https://doi.org/10.5177/ntvt.2018.11.18203

Serie: Medicamenten en mondzorg. Systematisch literatuuronderzoek naar effect van medicatie op de speekselklieren. / Wolff, Andy; Joshi, Revan Kumar; Ekström, Jörgen et al.
In: Nederlands Tijdschrift voor Tandheelkunde, Vol. 125, 2018, p. 593-601.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Communication

TY - JOUR

T1 - Serie: Medicamenten en mondzorg. Systematisch literatuuronderzoek naar effect van medicatie op de speekselklieren

AU - Wolff, Andy

AU - Joshi, Revan Kumar

AU - Ekström, Jörgen

AU - Aframian, Doron

AU - Pedersen, Anne Marie Lynge

AU - Proctor, Gordon

AU - Narayana, Nagamani

AU - Villa, Alessandro

AU - Sia, Ying Wai

AU - Aliko, Ardita

AU - McGowan, Richard

AU - Kerr, Alexander Ross

AU - Jensen, Siri Beier

AU - Vissink, Arjan

AU - Dawes, Colin

PY - 2018

Y1 - 2018

N2 - Evidence-based reviews of drugs causing medication-induced salivary gland dysfunction, such as xerostomia (sensation of oral dryness) and subjective sialorrhea are lacking. To compile a list of medicaments that influence salivary gland function, electronic databases were searched for relevant articles published up to June 2013. A total of 269 papers out of 3,867 records located satisfied the inclusion criteria (relevance, quality of methodology, strength of evidence). A total of 56 active substances with a higher level of evidence and 50 active substances with a moderate level of evidence of causing salivary gland dysfunction are described in this article. While xerostomia was a commonly reported outcome, the objective effect on salivary secretion was rarely measured. Xerostomia was, moreover, mostly reported as a negative side effect instead of the intended effect of that drug. A comprehensive list of medications having documented effects on salivary gland function or symptoms was compiled, which may assist practitioners in assessing patients who complain of dry mouth while taking medications.

AB - Evidence-based reviews of drugs causing medication-induced salivary gland dysfunction, such as xerostomia (sensation of oral dryness) and subjective sialorrhea are lacking. To compile a list of medicaments that influence salivary gland function, electronic databases were searched for relevant articles published up to June 2013. A total of 269 papers out of 3,867 records located satisfied the inclusion criteria (relevance, quality of methodology, strength of evidence). A total of 56 active substances with a higher level of evidence and 50 active substances with a moderate level of evidence of causing salivary gland dysfunction are described in this article. While xerostomia was a commonly reported outcome, the objective effect on salivary secretion was rarely measured. Xerostomia was, moreover, mostly reported as a negative side effect instead of the intended effect of that drug. A comprehensive list of medications having documented effects on salivary gland function or symptoms was compiled, which may assist practitioners in assessing patients who complain of dry mouth while taking medications.

U2 - 10.5177/ntvt.2018.11.18203

DO - 10.5177/ntvt.2018.11.18203

M3 - Tidsskriftartikel

C2 - 30457580

SN - 0028-2200

VL - 125

SP - 593

EP - 601

JO - Nederlands Tijdschrift voor Tandheelkunde

JF - Nederlands Tijdschrift voor Tandheelkunde

ER -