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Self-Assembly of DNA Origami and Single-Stranded Tile Structures at Room Temperature

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Efficient self-assembly: Self-assembly of DNA nanostructures at room temperature was achieved by incubating the component strands in the presence of a denaturing agent (30-40% formamide). This isothermal method is efficient for assembly of both DNA origami (purple, see scheme) and single-stranded tile (SST, blue) structures, as well as an SST ribbon growing on an origami template.
Original languageEnglish
JournalAngewandte Chemie International Edition
Pages (from-to)9219-9223
Number of pages5
Publication statusPublished - 26 Aug 2013

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