Secular trends in incidence and mortality of bacteraemia in a Danish county 1981-1994

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Secular trends in incidence and mortality of bacteraemia in a Danish county 1981-1994. / Madsen, Kreesten Meldgaard; Schønheyder, Henrik Carl; Kristensen, Brian; Sørensen, Henrik Toft.

In: Acta Pathologica Microbiologica et Immunologica Scandinavica, Vol. 107, No. 3, 03.1999, p. 346-352.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

Harvard

Madsen, KM, Schønheyder, HC, Kristensen, B & Sørensen, HT 1999, 'Secular trends in incidence and mortality of bacteraemia in a Danish county 1981-1994', Acta Pathologica Microbiologica et Immunologica Scandinavica, vol. 107, no. 3, pp. 346-352. https://doi.org/10.1111/j.1699-0463.1999.tb01563.x

APA

Madsen, K. M., Schønheyder, H. C., Kristensen, B., & Sørensen, H. T. (1999). Secular trends in incidence and mortality of bacteraemia in a Danish county 1981-1994. Acta Pathologica Microbiologica et Immunologica Scandinavica, 107(3), 346-352. https://doi.org/10.1111/j.1699-0463.1999.tb01563.x

CBE

Madsen KM, Schønheyder HC, Kristensen B, Sørensen HT. 1999. Secular trends in incidence and mortality of bacteraemia in a Danish county 1981-1994. Acta Pathologica Microbiologica et Immunologica Scandinavica. 107(3):346-352. https://doi.org/10.1111/j.1699-0463.1999.tb01563.x

MLA

Madsen, Kreesten Meldgaard et al. "Secular trends in incidence and mortality of bacteraemia in a Danish county 1981-1994". Acta Pathologica Microbiologica et Immunologica Scandinavica. 1999, 107(3). 346-352. https://doi.org/10.1111/j.1699-0463.1999.tb01563.x

Vancouver

Madsen KM, Schønheyder HC, Kristensen B, Sørensen HT. Secular trends in incidence and mortality of bacteraemia in a Danish county 1981-1994. Acta Pathologica Microbiologica et Immunologica Scandinavica. 1999 Mar;107(3):346-352. https://doi.org/10.1111/j.1699-0463.1999.tb01563.x

Author

Madsen, Kreesten Meldgaard ; Schønheyder, Henrik Carl ; Kristensen, Brian ; Sørensen, Henrik Toft. / Secular trends in incidence and mortality of bacteraemia in a Danish county 1981-1994. In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 1999 ; Vol. 107, No. 3. pp. 346-352.

Bibtex

@article{e024eb60954c11dabee902004c4f4f50,
title = "Secular trends in incidence and mortality of bacteraemia in a Danish county 1981-1994",
abstract = "We estimated the incidence and mortality of bacteraemia in the County of North Jutland and examined factors that could explain the changes observed. A population-based survey of bacteraemia was conducted in the Danish County of North Jutland during 1981-1994. Data were retrieved from a regional bacteraemia register. The mortality was determined through linkage to the Danish Civil Registration System. A total of 7198 bacteraemias were detected, and the annual incidence increased from 76 per 100,000 person-years in 1981 to 153 in 1994. One major determining factor was a change in blood culture system with a higher volume of blood per sample, but annual numbers of blood cultures also increased. The 30-day mortality rate increased from 17 to 40 per 100,000 person-years during the study period, whereas the case-fatality rate remained constant (23.6%; 95% confidence intervals 22.6%-24.6%). The number of bacteraemias increased significantly. This observation could be explained only partly by changes in demography, in blood culture system, and in diagnostic activity. The case fatality rate remained constant despite the fact that more people were diagnosed with bacteraemia; this indicates that, with recent blood culture practice, more clinically significant bacteraemias are diagnosed.",
keywords = "bacteraemia, septicaemia, epidemiology, incidence, mortality, case fatality",
author = "Madsen, {Kreesten Meldgaard} and Sch{\o}nheyder, {Henrik Carl} and Brian Kristensen and S{\o}rensen, {Henrik Toft}",
year = "1999",
month = mar,
doi = "10.1111/j.1699-0463.1999.tb01563.x",
language = "English",
volume = "107",
pages = "346--352",
journal = "A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica",
issn = "0903-4641",
publisher = "Wiley Online",
number = "3",

}

RIS

TY - JOUR

T1 - Secular trends in incidence and mortality of bacteraemia in a Danish county 1981-1994

AU - Madsen, Kreesten Meldgaard

AU - Schønheyder, Henrik Carl

AU - Kristensen, Brian

AU - Sørensen, Henrik Toft

PY - 1999/3

Y1 - 1999/3

N2 - We estimated the incidence and mortality of bacteraemia in the County of North Jutland and examined factors that could explain the changes observed. A population-based survey of bacteraemia was conducted in the Danish County of North Jutland during 1981-1994. Data were retrieved from a regional bacteraemia register. The mortality was determined through linkage to the Danish Civil Registration System. A total of 7198 bacteraemias were detected, and the annual incidence increased from 76 per 100,000 person-years in 1981 to 153 in 1994. One major determining factor was a change in blood culture system with a higher volume of blood per sample, but annual numbers of blood cultures also increased. The 30-day mortality rate increased from 17 to 40 per 100,000 person-years during the study period, whereas the case-fatality rate remained constant (23.6%; 95% confidence intervals 22.6%-24.6%). The number of bacteraemias increased significantly. This observation could be explained only partly by changes in demography, in blood culture system, and in diagnostic activity. The case fatality rate remained constant despite the fact that more people were diagnosed with bacteraemia; this indicates that, with recent blood culture practice, more clinically significant bacteraemias are diagnosed.

AB - We estimated the incidence and mortality of bacteraemia in the County of North Jutland and examined factors that could explain the changes observed. A population-based survey of bacteraemia was conducted in the Danish County of North Jutland during 1981-1994. Data were retrieved from a regional bacteraemia register. The mortality was determined through linkage to the Danish Civil Registration System. A total of 7198 bacteraemias were detected, and the annual incidence increased from 76 per 100,000 person-years in 1981 to 153 in 1994. One major determining factor was a change in blood culture system with a higher volume of blood per sample, but annual numbers of blood cultures also increased. The 30-day mortality rate increased from 17 to 40 per 100,000 person-years during the study period, whereas the case-fatality rate remained constant (23.6%; 95% confidence intervals 22.6%-24.6%). The number of bacteraemias increased significantly. This observation could be explained only partly by changes in demography, in blood culture system, and in diagnostic activity. The case fatality rate remained constant despite the fact that more people were diagnosed with bacteraemia; this indicates that, with recent blood culture practice, more clinically significant bacteraemias are diagnosed.

KW - bacteraemia

KW - septicaemia

KW - epidemiology

KW - incidence

KW - mortality

KW - case fatality

U2 - 10.1111/j.1699-0463.1999.tb01563.x

DO - 10.1111/j.1699-0463.1999.tb01563.x

M3 - Journal article

VL - 107

SP - 346

EP - 352

JO - A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica

JF - A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica

SN - 0903-4641

IS - 3

ER -