Abstract
Exposure to traffic noise may result in stress and sleep disturbances, which may impair the immune system. People with weakened immune systems are known to have a higher risk for non-Hodgkin lymphoma (NHL). We aimed to determine whether traffic noise was associated with risk for NHL. We identified 2,753 cases aged 30-84 years with a primary diagnosis of NHL in Denmark between 1992 and 2010. For each case we selected two random population controls, matched on sex and year of birth. Road traffic noise was calculated for all present and historical residential addresses of cases and controls from 1987 to 2010. Associations between traffic noise and risk for NHL were estimated using conditional logistic regression, adjusted for socioeconomic position. We found a 5-year time-weighted mean of road traffic noise above 65 dB to be associated with an 18% higher risk for NHL (95% confidence interval (CI) 1.01-1.37) when compared to road traffic noise below 55 dB, whereas for exposure between 55 and 65 dB no association was found. In analyses of NHL subtypes, we found no association between road traffic noise and risk for T-cell lymphoma, whereas increased risks for B-cell lymphoma and unspecified lymphomas were observed at exposures above 65 dB. In conclusion, our nationwide study may indicate that high exposure to traffic noise is associated with higher risk for NHL.
| Original language | English |
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| Title of host publication | Euronoise 2015 |
| Number of pages | 6 |
| Publication date | 2015 |
| Pages | 99-104 |
| Publication status | Published - 2015 |
| Event | 10th European Congress and Exposition on Noise Control Engineering, Euronoise 2015 - Maastricht, Netherlands Duration: 1 Jun 2015 → 3 Jun 2015 |
Conference
| Conference | 10th European Congress and Exposition on Noise Control Engineering, Euronoise 2015 |
|---|---|
| Country/Territory | Netherlands |
| City | Maastricht |
| Period | 01/06/2015 → 03/06/2015 |