TY - JOUR
T1 - Return to work following adverse cardiovascular events in adults with congenital heart disease
AU - Evers, Patrick D
AU - Körmendiné Farkas, Dóra
AU - Hjorth, Cathrine Fonnesbech
AU - Khoury, Michael
AU - Olsen, Morten
AU - Madsen, Nicolas
PY - 2021/3/1
Y1 - 2021/3/1
N2 - AbstractBackgroundAdults with congenital heart disease (CHD) are at increased risk for major adverse cardiovascular events (MACE), including stroke, myocardial infarctions, and heart failure. Following survival of MACE, an important metric is re-entry to the workforce. This study sought to characterize the differences in return-to-work (RTW) characteristics between MACE survivors with CHD and those in the general population.MethodsLinking Danish health and administrative registries, a cohort of adults with CHD who survived a MACE between the years of 1992–2017 were matched 10:1 by age at MACE, year of MACE, and sex to MACE survivors without CHD. Logistic regression assessed working status relative risk at three-, six-, and 12- months after the MACE event. Cox regression hazard ratio characterized time to RTW and maintained RTW.ResultsDuring the study period, 538 CHD patients survived MACE. These patients were matched to 4930 MACE survivors without CHD. The adjusted odds ratios of having returned to work were 0.91 (95% confidence interval (CI): 0.73–1.14) of employment at three months, 0.77 (95% CI: 0.61–0.96) at six months, and 0.76 (95% CI: 0.61–0.96) at 12 months. Of those who required governmental disability payments after MACE and admission for longer than one day, the adjusted hazard ratio of maintained RTW was 0.83 (95% CI: 0.69–0.99) for CHD patients compared to the general population.ConclusionsPatients with CHD who survive a MACE have evidence of impaired RTW compared to those without CHD. Further research is needed to understand and augment functional recovery in this complex population.
AB - AbstractBackgroundAdults with congenital heart disease (CHD) are at increased risk for major adverse cardiovascular events (MACE), including stroke, myocardial infarctions, and heart failure. Following survival of MACE, an important metric is re-entry to the workforce. This study sought to characterize the differences in return-to-work (RTW) characteristics between MACE survivors with CHD and those in the general population.MethodsLinking Danish health and administrative registries, a cohort of adults with CHD who survived a MACE between the years of 1992–2017 were matched 10:1 by age at MACE, year of MACE, and sex to MACE survivors without CHD. Logistic regression assessed working status relative risk at three-, six-, and 12- months after the MACE event. Cox regression hazard ratio characterized time to RTW and maintained RTW.ResultsDuring the study period, 538 CHD patients survived MACE. These patients were matched to 4930 MACE survivors without CHD. The adjusted odds ratios of having returned to work were 0.91 (95% confidence interval (CI): 0.73–1.14) of employment at three months, 0.77 (95% CI: 0.61–0.96) at six months, and 0.76 (95% CI: 0.61–0.96) at 12 months. Of those who required governmental disability payments after MACE and admission for longer than one day, the adjusted hazard ratio of maintained RTW was 0.83 (95% CI: 0.69–0.99) for CHD patients compared to the general population.ConclusionsPatients with CHD who survive a MACE have evidence of impaired RTW compared to those without CHD. Further research is needed to understand and augment functional recovery in this complex population.
KW - Congenital
KW - Heart defects
KW - Hospitalization
KW - Registries
UR - http://www.scopus.com/inward/record.url?scp=85153989464&partnerID=8YFLogxK
U2 - 10.1016/j.ijcchd.2021.100160
DO - 10.1016/j.ijcchd.2021.100160
M3 - Tidsskriftartikel
SN - 2666-6685
VL - 4
JO - International Journal of Cardiology Congenital Heart Disease
JF - International Journal of Cardiology Congenital Heart Disease
M1 - 100160
ER -