Relationship between radiobiological hypoxia and direct estimates of tumour oxygenation in a mouse tumour model

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Abstract

CDF1 mice were allowed to breathe either oxygen, carbogen or different concentrations of carbon monoxide gas. These treatments significantly altered the percentage of clonogenic hypoxic cells in a C3H mouse mammary carcinoma and these changes were found to correlate with direct measurements of tumour oxygenation obtained using an Eppendorf pO2 electrode.
Original languageEnglish
JournalRadiotherapy & Oncology
Volume28
Issue1
Pages (from-to)69-71
Number of pages3
ISSN0167-8140
Publication statusPublished - 1 Jul 1993

Keywords

  • Animals
  • Carbon Dioxide
  • Cell Hypoxia
  • Female
  • Male
  • Mammary Neoplasms, Experimental
  • Mice
  • Mice, Inbred Strains
  • Oxygen
  • Respiration

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