Regulation of sleep homeostasis by sexual arousal

TY - JOUR

T1 - Regulation of sleep homeostasis by sexual arousal

AU - Beckwith, Esteban J.

AU - Geissmann, Quentin

AU - French, Alice S.

AU - Gilestro, Giorgio F.

N1 - Publisher Copyright: © Beckwith et al.

PY - 2017/9/12

Y1 - 2017/9/12

N2 - In all animals, sleep pressure is under continuous tight regulation. It is universally accepted that this regulation arises from a two-process model, integrating both a circadian and a homeostatic controller. Here we explore the role of environmental social signals as a third, parallel controller of sleep homeostasis and sleep pressure. We show that, in Drosophila melanogaster males, sleep pressure after sleep deprivation can be counteracted by raising their sexual arousal, either by engaging the flies with prolonged courtship activity or merely by exposing them to female pheromones.

AB - In all animals, sleep pressure is under continuous tight regulation. It is universally accepted that this regulation arises from a two-process model, integrating both a circadian and a homeostatic controller. Here we explore the role of environmental social signals as a third, parallel controller of sleep homeostasis and sleep pressure. We show that, in Drosophila melanogaster males, sleep pressure after sleep deprivation can be counteracted by raising their sexual arousal, either by engaging the flies with prolonged courtship activity or merely by exposing them to female pheromones.

UR - http://www.scopus.com/inward/record.url?scp=85032949527&partnerID=8YFLogxK

U2 - 10.7554/eLife.27445

DO - 10.7554/eLife.27445

M3 - Journal article

C2 - 28893376

AN - SCOPUS:85032949527

SN - 2050-084X

VL - 6

JO - eLife

JF - eLife

M1 - e27445

ER -