Regional Gastrointestinal Motility in Healthy Children

Christian Emil Brinck; Esben Bolvig Mark; Cecilie Ejerskov; Klaus Birkelund Johansen; Nanna Sutter; Vincent Schlageter; Asbjørn Mohr Drewes; Klaus Krogh

doi:10.1097/MPG.0000000000003198

Regional Gastrointestinal Motility in Healthy Children

Christian Emil Brinck, Esben Bolvig Mark, Cecilie Ejerskov, Klaus Birkelund Johansen, Nanna Sutter, Vincent Schlageter, Asbjørn Mohr Drewes, Klaus Krogh

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

4 Citations (Scopus)

Abstract

OBJECTIVE: The aim of the study was to evaluate the safety and use of the 3D-Transit system (Motilis SA, Lausanne, Switzerland) and to describe regional gastrointestinal transit times, segmental colonic transit times, and colonic movement patterns in healthy children. METHODS: Twenty-one healthy children (11 girls, median age 10.5 years, range 7-15 years) were included. For evaluation of gastrointestinal transit times and colonic movement patterns, we used the minimally invasive electromagnetic 3D-Transit system. A small electromagnetic capsule (21.5 mm × 8.3 mm) was ingested and tracked through the gastrointestinal tract by a body-worn detector. Regional gastrointestinal transit times were assessed as time between capsule passage of anatomical landmarks. Colonic movement patterns were described and classified based on capsule movement velocity, direction, and distance. RESULTS: One child could not swallow the capsule and 20 children completed the study without any discomfort or side-effects. Median whole gut transit time was 33.6 (range 10.7-80.5) hours, median gastric emptying time was 1.9 (range 0.1-22.1) hours, median small intestinal transit time was 4.9 (range 1.1-15.1) hours, and median colonic transit time was 26.4 (range 6.8-74.5) hours. Median ascending colon/cecum transit time was 9.7 (range 0.3-48.1) hours, median transverse colon transit time was 5.6 (range 0.0-11.6) hours, median descending colon transit time was 2.6 (range 0.01-22.3) hours, and median sigmoid colon/rectum transit time was 7.5 (range 0.1-31.6) hours. Colonic movement patterns among children corresponded to those previously described in healthy adults. CONCLUSIONS: The 3D-Transit system is a well-tolerated and minimally invasive method for assessment of gastrointestinal motility in children.

Original language	English
Journal	Journal of Pediatric Gastroenterology and Nutrition
Volume	73
Issue	3
Pages (from-to)	306-313
Number of pages	8
ISSN	0277-2116
DOIs	https://doi.org/10.1097/MPG.0000000000003198
Publication status	Published - Sept 2021

Keywords

colonic movement patterns
colonic transit time
electromagnetic tracking
gastric emptying
small intestinal transit time

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10.1097/MPG.0000000000003198

Cite this

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title = "Regional Gastrointestinal Motility in Healthy Children",

abstract = "OBJECTIVE: The aim of the study was to evaluate the safety and use of the 3D-Transit system (Motilis SA, Lausanne, Switzerland) and to describe regional gastrointestinal transit times, segmental colonic transit times, and colonic movement patterns in healthy children. METHODS: Twenty-one healthy children (11 girls, median age 10.5 years, range 7-15 years) were included. For evaluation of gastrointestinal transit times and colonic movement patterns, we used the minimally invasive electromagnetic 3D-Transit system. A small electromagnetic capsule (21.5 mm × 8.3 mm) was ingested and tracked through the gastrointestinal tract by a body-worn detector. Regional gastrointestinal transit times were assessed as time between capsule passage of anatomical landmarks. Colonic movement patterns were described and classified based on capsule movement velocity, direction, and distance. RESULTS: One child could not swallow the capsule and 20 children completed the study without any discomfort or side-effects. Median whole gut transit time was 33.6 (range 10.7-80.5) hours, median gastric emptying time was 1.9 (range 0.1-22.1) hours, median small intestinal transit time was 4.9 (range 1.1-15.1) hours, and median colonic transit time was 26.4 (range 6.8-74.5) hours. Median ascending colon/cecum transit time was 9.7 (range 0.3-48.1) hours, median transverse colon transit time was 5.6 (range 0.0-11.6) hours, median descending colon transit time was 2.6 (range 0.01-22.3) hours, and median sigmoid colon/rectum transit time was 7.5 (range 0.1-31.6) hours. Colonic movement patterns among children corresponded to those previously described in healthy adults. CONCLUSIONS: The 3D-Transit system is a well-tolerated and minimally invasive method for assessment of gastrointestinal motility in children.",

keywords = "colonic movement patterns, colonic transit time, electromagnetic tracking, gastric emptying, small intestinal transit time",

author = "Brinck, {Christian Emil} and Mark, {Esben Bolvig} and Cecilie Ejerskov and Johansen, {Klaus Birkelund} and Nanna Sutter and Vincent Schlageter and Drewes, {Asbj{\o}rn Mohr} and Klaus Krogh",

note = "Publisher Copyright: Copyright {\textcopyright} 2021 by European Society for Pediatric Gastroenterology, Hepatology, and Nutrition and North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition.",

year = "2021",

month = sep,

doi = "10.1097/MPG.0000000000003198",

language = "English",

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pages = "306--313",

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Regional Gastrointestinal Motility in Healthy Children. / Brinck, Christian Emil; Mark, Esben Bolvig; Ejerskov, Cecilie et al.
In: Journal of Pediatric Gastroenterology and Nutrition, Vol. 73, No. 3, 09.2021, p. 306-313.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

TY - JOUR

T1 - Regional Gastrointestinal Motility in Healthy Children

AU - Brinck, Christian Emil

AU - Mark, Esben Bolvig

AU - Ejerskov, Cecilie

AU - Johansen, Klaus Birkelund

AU - Sutter, Nanna

AU - Schlageter, Vincent

AU - Drewes, Asbjørn Mohr

AU - Krogh, Klaus

N1 - Publisher Copyright: Copyright © 2021 by European Society for Pediatric Gastroenterology, Hepatology, and Nutrition and North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition.

PY - 2021/9

Y1 - 2021/9

N2 - OBJECTIVE: The aim of the study was to evaluate the safety and use of the 3D-Transit system (Motilis SA, Lausanne, Switzerland) and to describe regional gastrointestinal transit times, segmental colonic transit times, and colonic movement patterns in healthy children. METHODS: Twenty-one healthy children (11 girls, median age 10.5 years, range 7-15 years) were included. For evaluation of gastrointestinal transit times and colonic movement patterns, we used the minimally invasive electromagnetic 3D-Transit system. A small electromagnetic capsule (21.5 mm × 8.3 mm) was ingested and tracked through the gastrointestinal tract by a body-worn detector. Regional gastrointestinal transit times were assessed as time between capsule passage of anatomical landmarks. Colonic movement patterns were described and classified based on capsule movement velocity, direction, and distance. RESULTS: One child could not swallow the capsule and 20 children completed the study without any discomfort or side-effects. Median whole gut transit time was 33.6 (range 10.7-80.5) hours, median gastric emptying time was 1.9 (range 0.1-22.1) hours, median small intestinal transit time was 4.9 (range 1.1-15.1) hours, and median colonic transit time was 26.4 (range 6.8-74.5) hours. Median ascending colon/cecum transit time was 9.7 (range 0.3-48.1) hours, median transverse colon transit time was 5.6 (range 0.0-11.6) hours, median descending colon transit time was 2.6 (range 0.01-22.3) hours, and median sigmoid colon/rectum transit time was 7.5 (range 0.1-31.6) hours. Colonic movement patterns among children corresponded to those previously described in healthy adults. CONCLUSIONS: The 3D-Transit system is a well-tolerated and minimally invasive method for assessment of gastrointestinal motility in children.

AB - OBJECTIVE: The aim of the study was to evaluate the safety and use of the 3D-Transit system (Motilis SA, Lausanne, Switzerland) and to describe regional gastrointestinal transit times, segmental colonic transit times, and colonic movement patterns in healthy children. METHODS: Twenty-one healthy children (11 girls, median age 10.5 years, range 7-15 years) were included. For evaluation of gastrointestinal transit times and colonic movement patterns, we used the minimally invasive electromagnetic 3D-Transit system. A small electromagnetic capsule (21.5 mm × 8.3 mm) was ingested and tracked through the gastrointestinal tract by a body-worn detector. Regional gastrointestinal transit times were assessed as time between capsule passage of anatomical landmarks. Colonic movement patterns were described and classified based on capsule movement velocity, direction, and distance. RESULTS: One child could not swallow the capsule and 20 children completed the study without any discomfort or side-effects. Median whole gut transit time was 33.6 (range 10.7-80.5) hours, median gastric emptying time was 1.9 (range 0.1-22.1) hours, median small intestinal transit time was 4.9 (range 1.1-15.1) hours, and median colonic transit time was 26.4 (range 6.8-74.5) hours. Median ascending colon/cecum transit time was 9.7 (range 0.3-48.1) hours, median transverse colon transit time was 5.6 (range 0.0-11.6) hours, median descending colon transit time was 2.6 (range 0.01-22.3) hours, and median sigmoid colon/rectum transit time was 7.5 (range 0.1-31.6) hours. Colonic movement patterns among children corresponded to those previously described in healthy adults. CONCLUSIONS: The 3D-Transit system is a well-tolerated and minimally invasive method for assessment of gastrointestinal motility in children.

KW - colonic movement patterns

KW - colonic transit time

KW - electromagnetic tracking

KW - gastric emptying

KW - small intestinal transit time

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Regional Gastrointestinal Motility in Healthy Children

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