Rapid and Efficient Conversion of 11CO2 to 11CO through Silacarboxylic Acids: Applications in Pd-Mediated Carbonylations

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Rapid and Efficient Conversion of 11CO2 to 11CO through Silacarboxylic Acids : Applications in Pd-Mediated Carbonylations. / Nordeman, Patrik; Friis, Stig D.; Andersen, Thomas L.; Audrain, Helene; Larhed, Mats; Skrydstrup, Troels; Antoni, Gunnar.

In: Chemistry: A European Journal, Vol. 21, No. 49, 2015, p. 17601-17604.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

Harvard

Nordeman, P, Friis, SD, Andersen, TL, Audrain, H, Larhed, M, Skrydstrup, T & Antoni, G 2015, 'Rapid and Efficient Conversion of 11CO2 to 11CO through Silacarboxylic Acids: Applications in Pd-Mediated Carbonylations', Chemistry: A European Journal, vol. 21, no. 49, pp. 17601-17604. https://doi.org/10.1002/chem.201503262

APA

Nordeman, P., Friis, S. D., Andersen, T. L., Audrain, H., Larhed, M., Skrydstrup, T., & Antoni, G. (2015). Rapid and Efficient Conversion of 11CO2 to 11CO through Silacarboxylic Acids: Applications in Pd-Mediated Carbonylations. Chemistry: A European Journal, 21(49), 17601-17604. https://doi.org/10.1002/chem.201503262

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Author

Nordeman, Patrik ; Friis, Stig D. ; Andersen, Thomas L. ; Audrain, Helene ; Larhed, Mats ; Skrydstrup, Troels ; Antoni, Gunnar. / Rapid and Efficient Conversion of 11CO2 to 11CO through Silacarboxylic Acids : Applications in Pd-Mediated Carbonylations. In: Chemistry: A European Journal. 2015 ; Vol. 21, No. 49. pp. 17601-17604.

Bibtex

@article{f9bdbcb9f00b41bf9769a289158542f8,
title = "Rapid and Efficient Conversion of 11CO2 to 11CO through Silacarboxylic Acids: Applications in Pd-Mediated Carbonylations",
abstract = "Herein, we present a new rapid, efficient, and low-cost radiosynthetic protocol for the conversion of (CO2)-C-11 to (CO)-C-11 and its subsequent application in Pd-mediated reactions of importance for PET applications. This room-temperature methodology, using readily available chemical reagents, is carried out in simple glass vials, thus eliminating the need for expensive and specialized high-temperature equipment to access (CO)-C-11. With this fast and near-quantitative conversion of (CO2)-C-11 into (CO)-C-11, aryl and heteroaryl iodides were easily converted into a broad selection of biologically active amides in radiochemical yields ranging from 29-84 %.",
keywords = "carbon monoxide, carbon-11, carbon dioxide fixation, positron emission tomography, radiochemistry, POSITRON-EMISSION-TOMOGRAPHY, ARYL HALIDES, MONOXIDE, PET, COMPLEXES, CHEMISTRY, PRESSURE, KETONES",
author = "Patrik Nordeman and Friis, {Stig D.} and Andersen, {Thomas L.} and Helene Audrain and Mats Larhed and Troels Skrydstrup and Gunnar Antoni",
year = "2015",
doi = "10.1002/chem.201503262",
language = "English",
volume = "21",
pages = "17601--17604",
journal = "Chemistry: A European Journal",
issn = "0947-6539",
publisher = "Wiley - V C H Verlag GmbH & Co. KGaA",
number = "49",

}

RIS

TY - JOUR

T1 - Rapid and Efficient Conversion of 11CO2 to 11CO through Silacarboxylic Acids

T2 - Applications in Pd-Mediated Carbonylations

AU - Nordeman, Patrik

AU - Friis, Stig D.

AU - Andersen, Thomas L.

AU - Audrain, Helene

AU - Larhed, Mats

AU - Skrydstrup, Troels

AU - Antoni, Gunnar

PY - 2015

Y1 - 2015

N2 - Herein, we present a new rapid, efficient, and low-cost radiosynthetic protocol for the conversion of (CO2)-C-11 to (CO)-C-11 and its subsequent application in Pd-mediated reactions of importance for PET applications. This room-temperature methodology, using readily available chemical reagents, is carried out in simple glass vials, thus eliminating the need for expensive and specialized high-temperature equipment to access (CO)-C-11. With this fast and near-quantitative conversion of (CO2)-C-11 into (CO)-C-11, aryl and heteroaryl iodides were easily converted into a broad selection of biologically active amides in radiochemical yields ranging from 29-84 %.

AB - Herein, we present a new rapid, efficient, and low-cost radiosynthetic protocol for the conversion of (CO2)-C-11 to (CO)-C-11 and its subsequent application in Pd-mediated reactions of importance for PET applications. This room-temperature methodology, using readily available chemical reagents, is carried out in simple glass vials, thus eliminating the need for expensive and specialized high-temperature equipment to access (CO)-C-11. With this fast and near-quantitative conversion of (CO2)-C-11 into (CO)-C-11, aryl and heteroaryl iodides were easily converted into a broad selection of biologically active amides in radiochemical yields ranging from 29-84 %.

KW - carbon monoxide

KW - carbon-11

KW - carbon dioxide fixation

KW - positron emission tomography

KW - radiochemistry

KW - POSITRON-EMISSION-TOMOGRAPHY

KW - ARYL HALIDES

KW - MONOXIDE

KW - PET

KW - COMPLEXES

KW - CHEMISTRY

KW - PRESSURE

KW - KETONES

U2 - 10.1002/chem.201503262

DO - 10.1002/chem.201503262

M3 - Journal article

C2 - 26492852

VL - 21

SP - 17601

EP - 17604

JO - Chemistry: A European Journal

JF - Chemistry: A European Journal

SN - 0947-6539

IS - 49

ER -