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Quantum dot based DNA nanosensors for amplification-free detection of human topoisomerase I

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Quantum dot based DNA nanosensors for amplification-free detection of human topoisomerase I. / Jepsen, Morten Leth; Ottaviani, Alessio; Knudsen, Birgitta R.; Ho, Yi-Ping.

In: R S C Advances, Vol. 4, No. 5, 01.01.2014, p. 2491-2494.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

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Author

Jepsen, Morten Leth ; Ottaviani, Alessio ; Knudsen, Birgitta R. ; Ho, Yi-Ping. / Quantum dot based DNA nanosensors for amplification-free detection of human topoisomerase I. In: R S C Advances. 2014 ; Vol. 4, No. 5. pp. 2491-2494.

Bibtex

@article{19b97c56a34d4b68b41152a7d3d063d5,
title = "Quantum dot based DNA nanosensors for amplification-free detection of human topoisomerase I",
abstract = "We develop a quantum dot based DNA nanosensor specifically targeting the cleavage–religation activity of an essential DNA-modifying enzyme, human topoisomerase I. The assay has shown great promise in biological crude samples and thus is expected to contribute to clinical diagnostics and anti-cancer therapy",
author = "Jepsen, {Morten Leth} and Alessio Ottaviani and Knudsen, {Birgitta R.} and Yi-Ping Ho",
year = "2014",
month = "1",
day = "1",
doi = "10.1039/c3ra45557b",
language = "English",
volume = "4",
pages = "2491--2494",
journal = "R S C Advances",
issn = "2046-2069",
publisher = "RSC Publishing",
number = "5",

}

RIS

TY - JOUR

T1 - Quantum dot based DNA nanosensors for amplification-free detection of human topoisomerase I

AU - Jepsen, Morten Leth

AU - Ottaviani, Alessio

AU - Knudsen, Birgitta R.

AU - Ho, Yi-Ping

PY - 2014/1/1

Y1 - 2014/1/1

N2 - We develop a quantum dot based DNA nanosensor specifically targeting the cleavage–religation activity of an essential DNA-modifying enzyme, human topoisomerase I. The assay has shown great promise in biological crude samples and thus is expected to contribute to clinical diagnostics and anti-cancer therapy

AB - We develop a quantum dot based DNA nanosensor specifically targeting the cleavage–religation activity of an essential DNA-modifying enzyme, human topoisomerase I. The assay has shown great promise in biological crude samples and thus is expected to contribute to clinical diagnostics and anti-cancer therapy

U2 - 10.1039/c3ra45557b

DO - 10.1039/c3ra45557b

M3 - Journal article

AN - SCOPUS:84890282791

VL - 4

SP - 2491

EP - 2494

JO - R S C Advances

JF - R S C Advances

SN - 2046-2069

IS - 5

ER -