Quantitative Proteome Analysis Reveals Increased Content of Basement Membrane Proteins in Arteries From Patients With Type 2 Diabetes Mellitus and Lower Levels Among Metformin Users

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

    Simone A R Preil, From the Department of Biochemistry and Pharmacology, Odense University Hospital (S.A.R.P., L.P.K., H.C.B., P.S.J., M.B.-P., M.L.H., L.M.R.) and Protein Research Group, Department of Biochemistry and Molecular Biology (M.R.L.), University of Southern Denmark, Odense, Denmark; Center for Individualized Medicine in Arterial Diseases (CIMA), Center for Clinical Proteomics (CCP), Odense Patient Explorative Network (OPEN) (S.A.R.P., L.P.K., H.C.B., P.S.J., M.B.-P., M.L.H., L.M.R.) and Department of Cardiothoracic and Vascular Surgery (M.L.H.), Odense University Hospital, Odense, Denmark; and Institute of Pathology, Aarhus University Hospital, Aarhus, Denmark (P.S.N., T.S.).,
  • Lars P Kristensen
  • Hans C Beck, From the Department of Biochemistry and Pharmacology, Odense University Hospital (S.A.R.P., L.P.K., H.C.B., P.S.J., M.B.-P., M.L.H., L.M.R.) and Protein Research Group, Department of Biochemistry and Molecular Biology (M.R.L.), University of Southern Denmark, Odense, Denmark; Center for Individualized Medicine in Arterial Diseases (CIMA), Center for Clinical Proteomics (CCP), Odense Patient Explorative Network (OPEN) (S.A.R.P., L.P.K., H.C.B., P.S.J., M.B.-P., M.L.H., L.M.R.) and Department of Cardiothoracic and Vascular Surgery (M.L.H.), Odense University Hospital, Odense, Denmark; and Institute of Pathology, Aarhus University Hospital, Aarhus, Denmark (P.S.N., T.S.)., Pia S Jensen, From the Department of Biochemistry and Pharmacology, Odense University Hospital (S.A.R.P., L.P.K., H.C.B., P.S.J., M.B.-P., M.L.H., L.M.R.) and Protein Research Group, Department of Biochemistry and Molecular Biology (M.R.L.), University of Southern Denmark, Odense, Denmark; Center for Individualized Medicine in Arterial Diseases (CIMA), Center for Clinical Proteomics (CCP), Odense Patient Explorative Network (OPEN) (S.A.R.P., L.P.K., H.C.B., P.S.J., M.B.-P., M.L.H., L.M.R.) and Department of Cardiothoracic and Vascular Surgery (M.L.H.), Odense University Hospital, Odense, Denmark; and Institute of Pathology, Aarhus University Hospital, Aarhus, Denmark (P.S.N., T.S.).,
  • Patricia S Nielsen
  • Torben Steiniche
  • Marina Bjørling-Poulsen, From the Department of Biochemistry and Pharmacology, Odense University Hospital (S.A.R.P., L.P.K., H.C.B., P.S.J., M.B.-P., M.L.H., L.M.R.) and Protein Research Group, Department of Biochemistry and Molecular Biology (M.R.L.), University of Southern Denmark, Odense, Denmark; Center for Individualized Medicine in Arterial Diseases (CIMA), Center for Clinical Proteomics (CCP), Odense Patient Explorative Network (OPEN) (S.A.R.P., L.P.K., H.C.B., P.S.J., M.B.-P., M.L.H., L.M.R.) and Department of Cardiothoracic and Vascular Surgery (M.L.H.), Odense University Hospital, Odense, Denmark; and Institute of Pathology, Aarhus University Hospital, Aarhus, Denmark (P.S.N., T.S.)., Martin R Larsen, From the Department of Biochemistry and Pharmacology, Odense University Hospital (S.A.R.P., L.P.K., H.C.B., P.S.J., M.B.-P., M.L.H., L.M.R.) and Protein Research Group, Department of Biochemistry and Molecular Biology (M.R.L.), University of Southern Denmark, Odense, Denmark; Center for Individualized Medicine in Arterial Diseases (CIMA), Center for Clinical Proteomics (CCP), Odense Patient Explorative Network (OPEN) (S.A.R.P., L.P.K., H.C.B., P.S.J., M.B.-P., M.L.H., L.M.R.) and Department of Cardiothoracic and Vascular Surgery (M.L.H.), Odense University Hospital, Odense, Denmark; and Institute of Pathology, Aarhus University Hospital, Aarhus, Denmark (P.S.N., T.S.).,
  • Maria L Hansen
  • Lars M Rasmussen, From the Department of Biochemistry and Pharmacology, Odense University Hospital (S.A.R.P., L.P.K., H.C.B., P.S.J., M.B.-P., M.L.H., L.M.R.) and Protein Research Group, Department of Biochemistry and Molecular Biology (M.R.L.), University of Southern Denmark, Odense, Denmark; Center for Individualized Medicine in Arterial Diseases (CIMA), Center for Clinical Proteomics (CCP), Odense Patient Explorative Network (OPEN) (S.A.R.P., L.P.K., H.C.B., P.S.J., M.B.-P., M.L.H., L.M.R.) and Department of Cardiothoracic and Vascular Surgery (M.L.H.), Odense University Hospital, Odense, Denmark; and Institute of Pathology, Aarhus University Hospital, Aarhus, Denmark (P.S.N., T.S.). lars.melholt.rasmussen@rsyd.dk.
Original languageEnglish
JournalCirculation: Cardiovascular Genetics
Volume8
Issue number5
Pages (from-to)727-35
Number of pages9
ISSN1942-325X
DOIs
Publication statusPublished - Oct 2015
Externally publishedYes

    Research areas

  • Aged, Basement Membrane, Diabetes Mellitus, Type 2, Female, Humans, Hypoglycemic Agents, Male, Mammary Arteries, Membrane Proteins, Metformin, Proteome, Journal Article, Research Support, Non-U.S. Gov't

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