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Pulmonary gene silencing in transgenic EGFP mice using aerosolised chitosan/siRNA nanoparticles

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  • Department of Physics and Astronomy
  • Institute for Storage Ring Facilities - Aarhus (ISA)
  • Interdisciplinary Nanoscience Center
  • iNano-School
  • Department of Molecular Biology
  • Department of Molecular Biology
  • The Department of Cardiological Medicine B
This work describes the production and application of an aerosolised formulation of chitosan nanoparticles for improved pulmonary siRNA delivery and gene silencing in mice.
Original languageEnglish
JournalPharmaceutical Research
Pages (from-to)2520-7
Number of pages7
Publication statusPublished - 2010

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