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Pulmonary gene silencing in transgenic EGFP mice using aerosolised chitosan/siRNA nanoparticles
Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
- Ebbe J B Nielsen, Denmark
- Jan Møller Nielsen, Denmark
- Daniel Becker, Denmark
- Alexander Karlas, Denmark
- Hridayesh Prakash, Denmark
- Sys Z Glud
- Jonathan Merrison
- Flemming Besenbacher
- Thomas F Meyer, Denmark
- Jørgen Kjems
- Kenneth A Howard
- Department of Physics and Astronomy
- Institute for Storage Ring Facilities - Aarhus (ISA)
- Interdisciplinary Nanoscience Center
- iNano-School
- Department of Molecular Biology
- Department of Molecular Biology
- The Department of Cardiological Medicine B
This work describes the production and application of an aerosolised formulation of chitosan nanoparticles for improved pulmonary siRNA delivery and gene silencing in mice.
| Original language | English |
|---|---|
| Journal | Pharmaceutical Research |
| Volume | 27 |
| Issue | 12 |
| Pages (from-to) | 2520-7 |
| Number of pages | 7 |
| ISSN | 0724-8741 |
| DOIs | |
| Publication status | Published - 2010 |
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ID: 22880793