Pulmonary gene silencing in transgenic EGFP mice using aerosolised chitosan/siRNA nanoparticles

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  • Department of Physics and Astronomy
  • Institute for Storage Ring Facilities - Aarhus (ISA)
  • Interdisciplinary Nanoscience Center
  • iNano-School
  • Department of Molecular Biology
  • Department of Molecular Biology
  • The Department of Cardiological Medicine B
This work describes the production and application of an aerosolised formulation of chitosan nanoparticles for improved pulmonary siRNA delivery and gene silencing in mice.
Original languageEnglish
JournalPharmaceutical Research
Volume27
Issue12
Pages (from-to)2520-7
Number of pages7
ISSN0724-8741
DOIs
Publication statusPublished - 2010

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