Proteomics and the Characterization of Fatty Liver Metabolism in Early Lactation Dairy Cows

Research output: Contribution to book/anthology/report/proceedingBook chapterResearchpeer-review

Standard

Proteomics and the Characterization of Fatty Liver Metabolism in Early Lactation Dairy Cows. / Ingvartsen, Klaus Lønne; Kuhla, Björn.

Proteomics in Domestic Animals: from Farm to Systems Biology. ed. / Andre Martinho de Almeida; David Eckersall; Ingrid Miller. Springer, 2018. p. 219-231.

Research output: Contribution to book/anthology/report/proceedingBook chapterResearchpeer-review

Harvard

Ingvartsen, KL & Kuhla, B 2018, Proteomics and the Characterization of Fatty Liver Metabolism in Early Lactation Dairy Cows. in A Martinho de Almeida, D Eckersall & I Miller (eds), Proteomics in Domestic Animals: from Farm to Systems Biology. Springer, pp. 219-231. https://doi.org/10.1007/978-3-319-69682-9_11

APA

Ingvartsen, K. L., & Kuhla, B. (2018). Proteomics and the Characterization of Fatty Liver Metabolism in Early Lactation Dairy Cows. In A. Martinho de Almeida, D. Eckersall, & I. Miller (Eds.), Proteomics in Domestic Animals: from Farm to Systems Biology (pp. 219-231). Springer. https://doi.org/10.1007/978-3-319-69682-9_11

CBE

Ingvartsen KL, Kuhla B. 2018. Proteomics and the Characterization of Fatty Liver Metabolism in Early Lactation Dairy Cows. Martinho de Almeida A, Eckersall D, Miller I, editors. In Proteomics in Domestic Animals: from Farm to Systems Biology. Springer. pp. 219-231. https://doi.org/10.1007/978-3-319-69682-9_11

MLA

Ingvartsen, Klaus Lønne and Björn Kuhla "Proteomics and the Characterization of Fatty Liver Metabolism in Early Lactation Dairy Cows"., Martinho de Almeida, Andre Eckersall, David Miller, Ingrid (editors). Proteomics in Domestic Animals: from Farm to Systems Biology. Springer. 2018, 219-231. https://doi.org/10.1007/978-3-319-69682-9_11

Vancouver

Ingvartsen KL, Kuhla B. Proteomics and the Characterization of Fatty Liver Metabolism in Early Lactation Dairy Cows. In Martinho de Almeida A, Eckersall D, Miller I, editors, Proteomics in Domestic Animals: from Farm to Systems Biology. Springer. 2018. p. 219-231 https://doi.org/10.1007/978-3-319-69682-9_11

Author

Ingvartsen, Klaus Lønne ; Kuhla, Björn. / Proteomics and the Characterization of Fatty Liver Metabolism in Early Lactation Dairy Cows. Proteomics in Domestic Animals: from Farm to Systems Biology. editor / Andre Martinho de Almeida ; David Eckersall ; Ingrid Miller. Springer, 2018. pp. 219-231

Bibtex

@inbook{00230d1a3aa24dc1848b69243d41ac91,
title = "Proteomics and the Characterization of Fatty Liver Metabolism in Early Lactation Dairy Cows",
abstract = "The high-yielding dairy cow faces major adaptions during the transition period from late pregnancy to early lactation where physiological changes occur in support of the dramatically increase in milk yield. The coordinated physiological changes secure mobilization of nutrients and energy from the body tissue that, in part, covers the rapid increase in nutrient needs for milk production in early lactation. Large amounts of energy are released from fat tissue as non-esterified fatty acids (NEFAs) which together with a depressed increase in energy intake are bringing the cow into a state of negative energy balance. Approximately 25{\%} of the NEFA passes through the liver, where it is metabolized or esterified to triglyceride. When the latter becomes excessive, fatty liver or hepatic lipidosis generally as a subclinical disease state will occur. This chapter investigates realizations in the molecular factors potentially causing fatty liver in the transition cow discovered using proteomics.",
keywords = "Liver, Proteomics, Dairy cow, Negative energy balance, Macronutrient and energy metabolism, Oxidative stress response",
author = "Ingvartsen, {Klaus L{\o}nne} and Bj{\"o}rn Kuhla",
year = "2018",
month = "2",
day = "2",
doi = "10.1007/978-3-319-69682-9_11",
language = "English",
isbn = "978-3-319-69681-2",
pages = "219--231",
editor = "{Martinho de Almeida}, Andre and Eckersall, {David } and Miller, {Ingrid }",
booktitle = "Proteomics in Domestic Animals: from Farm to Systems Biology",
publisher = "Springer",

}

RIS

TY - CHAP

T1 - Proteomics and the Characterization of Fatty Liver Metabolism in Early Lactation Dairy Cows

AU - Ingvartsen, Klaus Lønne

AU - Kuhla, Björn

PY - 2018/2/2

Y1 - 2018/2/2

N2 - The high-yielding dairy cow faces major adaptions during the transition period from late pregnancy to early lactation where physiological changes occur in support of the dramatically increase in milk yield. The coordinated physiological changes secure mobilization of nutrients and energy from the body tissue that, in part, covers the rapid increase in nutrient needs for milk production in early lactation. Large amounts of energy are released from fat tissue as non-esterified fatty acids (NEFAs) which together with a depressed increase in energy intake are bringing the cow into a state of negative energy balance. Approximately 25% of the NEFA passes through the liver, where it is metabolized or esterified to triglyceride. When the latter becomes excessive, fatty liver or hepatic lipidosis generally as a subclinical disease state will occur. This chapter investigates realizations in the molecular factors potentially causing fatty liver in the transition cow discovered using proteomics.

AB - The high-yielding dairy cow faces major adaptions during the transition period from late pregnancy to early lactation where physiological changes occur in support of the dramatically increase in milk yield. The coordinated physiological changes secure mobilization of nutrients and energy from the body tissue that, in part, covers the rapid increase in nutrient needs for milk production in early lactation. Large amounts of energy are released from fat tissue as non-esterified fatty acids (NEFAs) which together with a depressed increase in energy intake are bringing the cow into a state of negative energy balance. Approximately 25% of the NEFA passes through the liver, where it is metabolized or esterified to triglyceride. When the latter becomes excessive, fatty liver or hepatic lipidosis generally as a subclinical disease state will occur. This chapter investigates realizations in the molecular factors potentially causing fatty liver in the transition cow discovered using proteomics.

KW - Liver

KW - Proteomics

KW - Dairy cow

KW - Negative energy balance

KW - Macronutrient and energy metabolism

KW - Oxidative stress response

UR - https://doi.org/10.1007/978-3-319-69682-9

U2 - 10.1007/978-3-319-69682-9_11

DO - 10.1007/978-3-319-69682-9_11

M3 - Book chapter

SN - 978-3-319-69681-2

SP - 219

EP - 231

BT - Proteomics in Domestic Animals: from Farm to Systems Biology

A2 - Martinho de Almeida, Andre

A2 - Eckersall, David

A2 - Miller, Ingrid

PB - Springer

ER -