Protein aggregation: Close encounters of the greasy kind

Daniel Otzen

doi:10.1038/nchembio.1759

Protein aggregation: Close encounters of the greasy kind

Interdisciplinary Nanoscience Center - INANO-MBG, iNANO-huset

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

3 Citations (Scopus)

Abstract

Aggregation of α-synuclein (αSN) is critical to the development of Parkinson's disease (PD), but the role of membranes in this process has been unclear and controversial. Galvagnion et al. demonstrate and model how lipids can stimulate αSN aggregation over a narrow range of lipid:protein stoichiometries

Original language	English
Journal	Nature Chemical Biology
Volume	11
Issue	3
Pages (from-to)	176-177
Number of pages	2
ISSN	1552-4450
DOIs	https://doi.org/10.1038/nchembio.1759
Publication status	Published - 17 Feb 2015

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title = "Protein aggregation: Close encounters of the greasy kind",

abstract = "Aggregation of α-synuclein (αSN) is critical to the development of Parkinson's disease (PD), but the role of membranes in this process has been unclear and controversial. Galvagnion et al. demonstrate and model how lipids can stimulate αSN aggregation over a narrow range of lipid:protein stoichiometries",

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Protein aggregation: Close encounters of the greasy kind

Abstract

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