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Production of antibody against C3c epitopes which are inaccessible on native C3

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Anti-C3c antiserum was induced by immunizing rabbits with autologous erythrocytes coated with human C3b/C3bi. By absorption with human plasma this antiserum was rendered specific for C3c epitopes which are not expressed on native C3. This specificity may be analogous to that of immunoconglutinin.
Original languageEnglish
JournalJournal of Immunological Methods
Pages (from-to)245-52
Number of pages8
Publication statusPublished - 1983

    Research areas

  • Animals, Antibodies, Antibody Formation, Complement C3, Complement C3c, Epitopes, Erythrocyte Membrane, Humans, Immunoelectrophoresis, Two-Dimensional, Rabbits

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