Prevalence and Geographical Distribution of Insulin Pump Therapy in the Central Denmark Region and its Association with Metabolic Parameters

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  • Ulla Kampmann
  • Lene Ring Madsen
  • ,
  • Lasse Bjerg
  • Daniel R Witte
  • Kjeld Hasselstrøm, Department of Internal Medicine, Regional Hospital Herning, 7400 Herning, Denmark.
  • ,
  • Torben Østergård
  • Kirsten Alstrup, Department of Internal Medicine, Randers Regional Hospital, Randers NØ, Denmark.
  • ,
  • Marianne Kleis Møller, Department of Internal Medicine, Horsens Regional Hospital, Horsens, Denmark.
  • ,
  • Dorrit Dylmer
  • ,
  • Klavs Würgler Hansen

AIMS: Insulin treatment in type 1 diabetes encompasses multiple daily insulin injections (MDI) or continuous subcutaneous insulin infusion (CSII). Both population-based studies and comparative studies regarding CSII use are sparse. The aim of the current study was to describe the prevalence and distribution of CSII use among adults with type 1 diabetes in the Central Denmark Region and to compare metabolic control in CSII-treated patients to those treated with MDI.

METHODS: A database was constructed using the Danish Adult Diabetes Registry in 2014/2015 in combination with an audit of the patients' medical records.

RESULTS: 3909 adults with type 1 diabetes patients were included. The proportion of patients treated with CSII differed significantly between the 8 regional hospitals from 12.0 % to 31.1 %. CSII users had a significantly lower HbA1c compared to MDI treated patients (7.6 % (60 mmol/mol) versus 8.0 % (64 mmol/mol)) in unadjusted analyses. After adjustment for clinically relevant characteristics the difference between CSII and MDI-treated patients was attenuated, but remained statistically significant.

CONCLUSION: The distribution of CSII differed markedly between hospitals and CSII users had better glycemic control, even after adjustment for sex, age, BMI, diabetes duration, smoking, use of lipid-lowering and blood pressure-lowering medication.

Original languageEnglish
JournalDiabetes Research and Clinical Practice
Pages (from-to)148-155
Number of pages8
Publication statusPublished - Jul 2018

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