Preceding symptoms and temporal development of cortical superficial siderosis in cerebral amyloid angiopathy: a case report

Naja H. Andersen; Rolf A. Blauenfeldt; Ronni Mikkelsen; Claus Z. Simonsen

doi:10.1186/s12883-023-03300-9

Preceding symptoms and temporal development of cortical superficial siderosis in cerebral amyloid angiopathy: a case report

Naja H. Andersen^*, Rolf A. Blauenfeldt, Ronni Mikkelsen, Claus Z. Simonsen

^*Corresponding author for this work

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

Abstract

Background: We present a case illustrating evolution of symptoms and brain magnetic resonance imaging in cortical superficial siderosis. Case presentation: A 74-year-old man with no prior medical history presented with transient focal neurological episodes with subtle imaging changes. There was no evidence of cortical superficial siderosis. Two weeks later, the patient was readmitted with new episodes, and had developed cortical superficial siderosis adjacent to a cerebral microbleed. Transient focal neurological episode secondary to cortical superficial siderosis was diagnosed together with probable cerebral amyloid angiopathy. Conclusion: Clinical symptoms may precede the development of cortical superficial siderosis prior to being detectable on brain MRI. This case highlights the temporal development of cortical superficial siderosis.

Original language	English
Article number	252
Journal	BMC Neurology
Volume	23
Issue	1
Number of pages	4
ISSN	1471-2377
DOIs	https://doi.org/10.1186/s12883-023-03300-9
Publication status	Published - Dec 2023

Keywords

Amyloid spells
Brain magnetic resonance imaging
Case report
Cerebral amyloid angiopathy
Cortical superficial siderosis

Access to Document

10.1186/s12883-023-03300-9Licence: CC BY

Library access?

Check availability with the Royal Danish Library

Cite this

@article{0f6284e05b2446089c9b1ce1bb60c455,

title = "Preceding symptoms and temporal development of cortical superficial siderosis in cerebral amyloid angiopathy: a case report",

abstract = "Background: We present a case illustrating evolution of symptoms and brain magnetic resonance imaging in cortical superficial siderosis. Case presentation: A 74-year-old man with no prior medical history presented with transient focal neurological episodes with subtle imaging changes. There was no evidence of cortical superficial siderosis. Two weeks later, the patient was readmitted with new episodes, and had developed cortical superficial siderosis adjacent to a cerebral microbleed. Transient focal neurological episode secondary to cortical superficial siderosis was diagnosed together with probable cerebral amyloid angiopathy. Conclusion: Clinical symptoms may precede the development of cortical superficial siderosis prior to being detectable on brain MRI. This case highlights the temporal development of cortical superficial siderosis.",

keywords = "Amyloid spells, Brain magnetic resonance imaging, Case report, Cerebral amyloid angiopathy, Cortical superficial siderosis",

author = "Andersen, \{Naja H.\} and Blauenfeldt, \{Rolf A.\} and Ronni Mikkelsen and Simonsen, \{Claus Z.\}",

note = "Publisher Copyright: {\textcopyright} 2023, The Author(s).",

year = "2023",

month = dec,

doi = "10.1186/s12883-023-03300-9",

language = "English",

volume = "23",

journal = "BMC Neurology",

issn = "1471-2377",

publisher = "BioMed Central",

number = "1",

}

Preceding symptoms and temporal development of cortical superficial siderosis in cerebral amyloid angiopathy: a case report. / Andersen, Naja H.; Blauenfeldt, Rolf A.; Mikkelsen, Ronni et al.
In: BMC Neurology, Vol. 23, No. 1, 252, 12.2023.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

TY - JOUR

T1 - Preceding symptoms and temporal development of cortical superficial siderosis in cerebral amyloid angiopathy

T2 - a case report

AU - Andersen, Naja H.

AU - Blauenfeldt, Rolf A.

AU - Mikkelsen, Ronni

AU - Simonsen, Claus Z.

PY - 2023/12

Y1 - 2023/12

N2 - Background: We present a case illustrating evolution of symptoms and brain magnetic resonance imaging in cortical superficial siderosis. Case presentation: A 74-year-old man with no prior medical history presented with transient focal neurological episodes with subtle imaging changes. There was no evidence of cortical superficial siderosis. Two weeks later, the patient was readmitted with new episodes, and had developed cortical superficial siderosis adjacent to a cerebral microbleed. Transient focal neurological episode secondary to cortical superficial siderosis was diagnosed together with probable cerebral amyloid angiopathy. Conclusion: Clinical symptoms may precede the development of cortical superficial siderosis prior to being detectable on brain MRI. This case highlights the temporal development of cortical superficial siderosis.

AB - Background: We present a case illustrating evolution of symptoms and brain magnetic resonance imaging in cortical superficial siderosis. Case presentation: A 74-year-old man with no prior medical history presented with transient focal neurological episodes with subtle imaging changes. There was no evidence of cortical superficial siderosis. Two weeks later, the patient was readmitted with new episodes, and had developed cortical superficial siderosis adjacent to a cerebral microbleed. Transient focal neurological episode secondary to cortical superficial siderosis was diagnosed together with probable cerebral amyloid angiopathy. Conclusion: Clinical symptoms may precede the development of cortical superficial siderosis prior to being detectable on brain MRI. This case highlights the temporal development of cortical superficial siderosis.

KW - Amyloid spells

KW - Brain magnetic resonance imaging

KW - Case report

KW - Cerebral amyloid angiopathy

KW - Cortical superficial siderosis

UR - http://www.scopus.com/inward/record.url?scp=85163773358&partnerID=8YFLogxK

U2 - 10.1186/s12883-023-03300-9

DO - 10.1186/s12883-023-03300-9

M3 - Journal article

C2 - 37391707

AN - SCOPUS:85163773358

SN - 1471-2377

VL - 23

JO - BMC Neurology

JF - BMC Neurology

IS - 1

M1 - 252

ER -

Preceding symptoms and temporal development of cortical superficial siderosis in cerebral amyloid angiopathy: a case report

Abstract

Keywords

Access to Document

Library access?

Other files and links

Fingerprint

Cite this