Polymorphisms in the MASP1 gene are associated with serum levels of MASP-1, MASP-3, and MAp44

Christian Gytz Ammitzbøll; Rudi Steffensen; Hans Jørgen Nielsen; Steffen Thiel; Kristian Stengaard-Pedersen; Martin Bøgsted; Jens Christian Jensenius

doi:10.1371/journal.pone.0073317

Polymorphisms in the MASP1 gene are associated with serum levels of MASP-1, MASP-3, and MAp44

Christian Gytz Ammitzbøll, Rudi Steffensen, Hans Jørgen Nielsen, Steffen Thiel, Kristian Stengaard-Pedersen, Martin Bøgsted, Jens Christian Jensenius

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

Abstract

MASP-1 is the first protein in the activation of the lectin pathway and MASP-1 is, like its isoforms MASP-3 and MAp44, encoded by the MASP1 gene. Our aim was to explore associations between polymorphisms in MASP1 and corresponding concentrations of MASP-1, MASP-3, and MAp44 in plasma as well as the genetic contribution to the equilibrium between the three proteins.

Original language	English
Journal	PLOS ONE
Volume	8
Issue	9
Pages (from-to)	e73317
ISSN	1932-6203
DOIs	https://doi.org/10.1371/journal.pone.0073317
Publication status	Published - 2013

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title = "Polymorphisms in the MASP1 gene are associated with serum levels of MASP-1, MASP-3, and MAp44",

abstract = "MASP-1 is the first protein in the activation of the lectin pathway and MASP-1 is, like its isoforms MASP-3 and MAp44, encoded by the MASP1 gene. Our aim was to explore associations between polymorphisms in MASP1 and corresponding concentrations of MASP-1, MASP-3, and MAp44 in plasma as well as the genetic contribution to the equilibrium between the three proteins.",

author = "{Gytz Ammitzb{\o}ll}, Christian and Rudi Steffensen and {J{\o}rgen Nielsen}, Hans and Steffen Thiel and Kristian Stengaard-Pedersen and Martin B{\o}gsted and Jensenius, {Jens Christian}",

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T1 - Polymorphisms in the MASP1 gene are associated with serum levels of MASP-1, MASP-3, and MAp44

AU - Gytz Ammitzbøll, Christian

AU - Steffensen, Rudi

AU - Jørgen Nielsen, Hans

AU - Thiel, Steffen

AU - Stengaard-Pedersen, Kristian

AU - Bøgsted, Martin

AU - Jensenius, Jens Christian

PY - 2013

Y1 - 2013

N2 - MASP-1 is the first protein in the activation of the lectin pathway and MASP-1 is, like its isoforms MASP-3 and MAp44, encoded by the MASP1 gene. Our aim was to explore associations between polymorphisms in MASP1 and corresponding concentrations of MASP-1, MASP-3, and MAp44 in plasma as well as the genetic contribution to the equilibrium between the three proteins.

AB - MASP-1 is the first protein in the activation of the lectin pathway and MASP-1 is, like its isoforms MASP-3 and MAp44, encoded by the MASP1 gene. Our aim was to explore associations between polymorphisms in MASP1 and corresponding concentrations of MASP-1, MASP-3, and MAp44 in plasma as well as the genetic contribution to the equilibrium between the three proteins.

U2 - 10.1371/journal.pone.0073317

DO - 10.1371/journal.pone.0073317

M3 - Journal article

C2 - 24023860

SN - 1932-6203

VL - 8

SP - e73317

JO - PLOS ONE

JF - PLOS ONE

IS - 9

ER -

Polymorphisms in the MASP1 gene are associated with serum levels of MASP-1, MASP-3, and MAp44

Abstract

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