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Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders

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DOI

  • Daniel J Weiner, Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
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  • Emilie M Wigdor, Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
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  • Stephan Ripke, Department of Psychiatry and Psychotherapy, Charité-University Medicine Berlin, Campus Mitte, Berlin, Germany.
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  • Raymond K Walters, 1] Analytical and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA [2] Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
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  • Jack A Kosmicki, Program in Genetics and Genomics, Biological and Biomedical Sciences, Harvard Medical School, Boston, Massachusetts, USA.
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  • Jakob Grove
  • Kaitlin E Samocha, Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
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  • Jacqueline I Goldstein, Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
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  • Aysu Okbay, Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
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  • Jonas Bybjerg-Grauholm, Danish Center for Neonatal Screening, Department for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark.
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  • Thomas Werge, Department of Cardiology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark Danish Arrhythmia Research Centre, University of Copenhagen, Copenhagen, Denmark.
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  • David M Hougaard, Danish Center for Neonatal Screening, Department for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark.
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  • Jacob Taylor, Department of Psychiatry, Brigham and Women's Hospital, Boston, Massachusetts, USA.
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  • David Skuse, Behavioural Sciences Unit, Institute of Child Health, University College London, London, UK.
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  • Bernie Devlin, Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
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  • Richard Anney, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, Wales, UK.
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  • Stephan J Sanders, Department of Psychiatry, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, California, USA.
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  • Somer Bishop, Department of Psychiatry, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, California, USA.
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  • Preben Bo Mortensen
  • Anders D Børglum
  • George Davey Smith, Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
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  • Mark J Daly, Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
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  • Elise B Robinson, Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
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  • iPSYCH-Broad Autism Group
Original languageEnglish
JournalNature Genetics
Volume49
Issue7
Pages (from-to)978-985
ISSN1061-4036
DOIs
Publication statusPublished - 15 May 2017

    Research areas

  • Journal Article

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